Awareness information, information about others' presence and activities that allows us to determine their availability for conversation, plays an important role in workplace communication, as people often gather and act on it in the process of negotiating mutual availability. This paper presents a laboratory experiment examining how gathering awareness information is affected by the cultural backgrounds and mutual familiarity of collaborators. Results suggest that members of cultures considered more relationship-oriented (e.g., China) gathered awareness information less frequently than members of cultures that are more task-oriented (e.g., the United States). We argue that this is because of the different motivations for interaction prioritized by these cultures. We did not find any effect for familiarity, but provide several alternative explanations for this result. We argue that members of these cultures may therefore differ in the extent and frequency of their use of awareness information.Additionally, people develop different levels of familiarity with their collaborators: some may be more familiar because they have been working or spending some time together; others may be complete strangers with no previous interaction history. Research suggests people interact with strangers and nonstrangers differently, in that they are more informal and less polite when they are interacting with a friend than with a stranger (Brown & Levinson, 1987;Wolfson, 1988). These behavioral differences may also be reflected in how people gather awareness information about their collaborators. Since gathering awareness information is socially delicate and can be perceived as invasive and impolite, we argue that people will gather awareness information more frequently from people they know rather than from strangers.These two factors, cultural background and familiarity, are not only important individually, but also act together. Research suggests Americans and Chinese may differ in the ways they treat strangers and friends/acquaintances, in that Chinese may become less relationship-oriented when they are interacting with strangers than with friends, whereas no study has documented similar tendency for Americans (Tickle-Degnen & Rosenthal, 1990;Yang, 1995). Understanding and acknowledging the potential differences caused by culture, familiarity, and their interaction will not only help researchers develop and evaluate systems in a value-sensitive way, but also shed light on how relational closeness impact people's collaboration.The present study examines how different cultural values and relational familiarity affect how people gather awareness information in a simulated work environment. We found that American and Chinese users did use the same system, OpenMessenger, differently in terms of frequency of gathering awareness information. Contrary to our expectation, no difference was found along the familiarity dimension.