“…These deficits often precede the emergence of clinical symptoms, and are relatively stable during the course of schizophrenia and bipolar disorder (Hill et al, 2008; Kuswanto et al, 2015a; Kuswanto et al, 2015b). Epidemiological and clinical studies have also consistently highlighted the impact of stress-related environmental risk factors, including childhood trauma (CT) or childhood adversity (including physical abuse, physical neglect, emotional abuse, emotional neglect and sexual abuse) (Day et al, 1987; Lataster et al, 2012; Mayo et al, 2017; Holtzman et al, 2013; Bechdolf et al, 2010; Gershon et al, 2013; Thompson et al, 2009; van Os et al, 2010; Walder et al, 2014), urbanicity (McGrath et al, 2004; Newbury et al, 2017), and cannabis use (Murray et al, 2017) in the development of psychosis (Aiello et al, 2012; Fusar-Poli et al, 2017; Misiak et al, 2017).…”