Docosahexaenoic Acid and Arachidonic Acid Nutrition in Early Development

Carlson, Susan E.; Colombo, John

doi:10.1016/j.yapd.2016.04.011

Cited by 111 publications

(78 citation statements)

References 114 publications

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“…53,54 Infants that are fed formulas that are fortified with DHA and AA have lower incidences of upper respiratory infections and allergies, bronchitis, nasal congestion, cough, diarrhea that requires medical attention, atopic dermatitis, eczema, and contact dermatitis. [55][56][57] Although the concentration of n-6 and n-3 PUFAs in human milk varies highly depending on maternal diet, 52 there is insufficient data that supports the addition of DHA to formula without AA as well. 50 Infant formulas that include AA and DHA have beneficial effects on the immune system of developing infants.…”

Section: Polyunsaturated Fatty Acidsmentioning

confidence: 99%

<p>Insights into Novel Infant Milk Formula Bioactives</p>

Skolnick¹,

Chou²,

Miklavcic³

2020

NDS

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Human milk provides optimal infant nutrition for early life development. However, there are situations in which human milk feeding is not the most viable option for infant nutrition. Some factors include maternal illness, lactation insufficiency, storage complications, and time constraints. As a result, modern infant formula has become a substitute or alternative when breastfeeding is not possible or is inadequate for infants. In the optimal design of formula, many factors are considered in creating a product that is safe and provides a nutritional profile either equivalent to human milk or in optimal alignment with infant needs. Human milk composition serves as a reference for infant formula formulation. The purpose of this literature review is to provide a synopsis of recent advances in infant formula research in the past 5 years (2014)(2015)(2016)(2017)(2018). Specifically, the breadth of bioactive components of human milk that are not yet available in infant formulas and dose optimization requirements in full-term infants are reviewed. The nutritional value of infant formulas has been improved by adding functional bioactive ingredients such as choline, strains of probiotics, and prebiotic oligosaccharides. There are considerable variations in the composition of available infant formulas between manufacturers and across different countries. Formulas still generally lack important contents such as antibodies and exosomes that are present in human milk. Some of the adverse health outcomes associated with formula feeding as compared with human milk feeding are attributed to the different composition of the foods. This literature review summarizes the most recent research aimed at advancing infant formula composition to narrow the difference in health outcomes between human milk and formula-fed infants.

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Section: Polyunsaturated Fatty Acidsmentioning

confidence: 99%

<p>Insights into Novel Infant Milk Formula Bioactives</p>

Skolnick¹,

Chou²,

Miklavcic³

2020

NDS

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“…EPA-rich oils are mainly used in combination with DHA for infant formulation or dietary supplements (single cell oils). Additionally, EPA is used in aquaculture for fish-farming (Salmon farming) that plays a crucial role in their juvenile development [13,45].…”

Section: Omega-3 Fatty Acidsmentioning

confidence: 99%

The Impact of Microalgae in Food Science and Technology

Matos

2017

J Americ Oil Chem Soc

167

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Microalgae (including cyanobacteria) are promising organisms for sustainable products for use as feedstocks for food, feed, fine chemicals, and biofuels. They can synthesize a broad range of products with medium‐ to high‐value market price such as β‐1,3‐glucan polysaccharide, single‐cell‐protein, carotenoids and phycobilin pigments, and long‐chain polyunsaturated fatty acids that are commercialized in the food industry as dietary supplements and functional foods, in the pharmaceutical and chemical industries as cosmaceuticals and flavorants, and in the therapeutic field as nutraceutical compounds. These microorganisms are also exceptional producers of omega‐3 and omega‐6 fatty acids such as eicosapentaenoic, docosahexaenoic, and arachidonic acids that have been linked to several human health benefits. The aim of this paper is to review the main existing high‐value products that can be derived from microalgae with a particular focus on food science and technology applications. It also describes the gross and fine chemical composition of various algal species and details the nutritive importance of selected constituents. Finally, nutritional quality standards and legislative provisions to ensure food safety in the use of algal biomass are presented.

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“…As to be expected, omega-3 FA play a role in this important early period of life, too. Several studies indicate that the intake of α-linolenic acid (ALA) can alter the concentration of both ω-6 and ω-3 fatty acids in both mother and offspring with consequences on postnatal brain development [57][58][59]. Omega-3 supplementation is associated with a lower risk of spontaneous preterm delivery in smokers and low birth weight is also less frequent in smokers receiving omega-3 supplementation [60].…”

Section: Evolutionary Aspects Of Omega-3 Fatty Acidsmentioning

confidence: 99%

Proceedings of the 5th annual symposium of the German Society for Paleo Nutrition held in 2017

Steger¹

2017

jevohealth

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Docosahexaenoic Acid and Arachidonic Acid Nutrition in Early Development

Cited by 111 publications

References 114 publications

<p>Insights into Novel Infant Milk Formula Bioactives</p>

<p>Insights into Novel Infant Milk Formula Bioactives</p>

The Impact of Microalgae in Food Science and Technology

Proceedings of the 5th annual symposium of the German Society for Paleo Nutrition held in 2017

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