¿Doctor, porqué soy celíaco si soy mexicano? Rompiendo un paradigma más de la enfermedad celíaca en México

Remes-Troche, José María

doi:10.1016/j.rgmx.2018.03.001

Cited by 2 publications

(2 citation statements)

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“…In México, CD has a prevalence of ~1% (~1.2 million people) [ 22 ], yet we know very little about CD in terms of its genetic predisposition, clinical presentation, treatment and involvement of the gut microbiota in Mexican patients [ 17 , 23 , 24 , 25 , 26 , 27 ]. The purpose of this research is to investigate the gut microbiota composition and predicted functional profile in Mexican patients with GRDs.…”

Section: Introductionmentioning

confidence: 99%

First Insights into the Gut Microbiota of Mexican Patients with Celiac Disease and Non-Celiac Gluten Sensitivity

et al. 2018

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Gluten-related disorders (GRDs) are common chronic enteropathies and increasing evidence suggests an involvement of the gut microbiota. We examined the gut microbiota in Mexican people afflicted with GRDs. Ultra-high-throughput 16S marker sequencing was used to deeply describe the duodenal and fecal microbiota of patients with celiac disease (CD, n = 6), non-celiac gluten sensitivity (NCGS, n = 12), and healthy subjects (n = 12) from our local area. Additionally, we also investigated the changes in gut microbiota after four weeks on a gluten-free diet (GFD) in a subset of patients from whom paired samples were available. Despite a high inter-individual variability, significant differences in various microbial populations were identified. The linear discriminant analysis (LDA) effect size (LEfSe) method revealed that the genus Actinobacillus and the family Ruminococcaceae were higher in the duodenal and fecal microbiota of NCGS patients, respectively, while Novispirillum was higher in the duodenum of CD patients (p < 0.05, LDA score > 3.5). Interestingly, paired samples from NCGS patients showed a significant difference in duodenal Pseudomonas between the baseline period (median: 1.3%; min/max: 0.47–6.8%) and the period after four weeks on GFD (14.8%; 2.3–38.5%, p < 0.01, Wilcoxon signed-rank test). These results encourage more research on GRDs in México.

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Section: Introductionmentioning

confidence: 99%

First Insights into the Gut Microbiota of Mexican Patients with Celiac Disease and Non-Celiac Gluten Sensitivity

et al. 2018

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“…(10) .También España, Italia, Reino Unido, Alemania y Francia alcanzan altos índices. En otros países europeos como Holanda, Suecia, Portugal, Estonia y Rumania ha sido identificada con similares resultados (10,(18)(19)(20) . Actualmente en España la prevalencia es de 1/118 en la población infantil y de 1/389 en la adulta (21,22) .…”

Section: Epidemiologíaunclassified

Celiac disease in children. New challenges

Castañeda Guillot

2016

Rev Peru Pediatr

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Se expone las características de la enfermedad celíaca y los retos de su identificación. Se describe la prevalencia, patogenia, criterios recientes relacionados con las manifestaciones clínicas, asociaciones y complicaciones de la enfermedad. Se enfatiza el estado actual de su diagnóstico en los países andinos, los aspectos usados para su identificación y evaluación en la infancia y trascendencia a la adherencia del tratamiento por ser una enfermedad para toda la vida.destacándose el rol de la madre y su tarea de crianza como base de la salud mental de su bebé.

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¿Doctor, porqué soy celíaco si soy mexicano? Rompiendo un paradigma más de la enfermedad celíaca en México

Cited by 2 publications

References 7 publications

First Insights into the Gut Microbiota of Mexican Patients with Celiac Disease and Non-Celiac Gluten Sensitivity

First Insights into the Gut Microbiota of Mexican Patients with Celiac Disease and Non-Celiac Gluten Sensitivity

Celiac disease in children. New challenges

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