Doença arterial coronariana em diabéticas do tipo 2 assintomáticas: estudo comparativo entre o teste ergométrico, o teste cardiopulmonar e a cintilografia de perfusão miocárdica com dipiridamol na identificação de isquemia

Smanio, Paola Emanuela Poggio; Carvalho, Antônio Carlos; Tebexreni, Antônio Sérgio; Thom, A.; Rodrigues, F.P.; Meneghelo, Romeu Sérgio; Mastrocolla, Luiz Eduardo; Alves, Alexandre; Piegas, Leopoldo Soares; Paola, Ângelo Amato Vincenzo de

doi:10.1590/s0066-782x2007001700003

Cited by 9 publications

(3 citation statements)

References 27 publications

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“…Such data are in accordance with those of the literature. Smanio et al 11 , studying the MPS of 104 asymptomatic diabetic women, have reported myocardial ischemia in 34 (32.7%).…”

Section: Discussionmentioning

confidence: 99%

“…Exercise testing is known to have lower sensitivity and specificity in the female sex than in the male sex 18 . The sensitivity and specificity of the pharmacological or exercise stress tests can be improved by imaging methods that increase diagnostic accuracy 10,11,18 . With the refinement of the technique, a reduction in attenuation artifacts (breast, for example) was observed, leading to greater specificity 13 .…”

Section: Discussionmentioning

confidence: 99%

“…Myocardial perfusion scintigraphy (MPS) has become a highly important tool for diagnostic investigation in the female sex, particularly in women with unspecific alterations on baseline electrocardiogram and with low functional capacity or difficulty to achieve the proper heart rate, which is very common in the group of diabetic women and those with peripheral vascular disease 11,12 . In addition, the reduction in breast attenuation artifacts and the acquisition of images guided by electrocardiography (gated-SPECT) increase the accuracy of the test, helping to differentiate real defects and artifacts 13 .…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of Ischemia on Myocardial Perfusion Scintigraphy of Pre- and Postmenopausal Women

Santos¹,

Navarro²,

Alexandre³

et al. 2013

Arquivos Brasileiros De Cardiologia

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BackgroundIn postmenopausal women, the presence of risk factors for coronary artery disease (CAD) increases. However, the difference in prevalence of ischemia between pre- and postmenopausal women with multiple risk factors for CAD has not been well established.ObjectivesTo compare the prevalence of ischemia on Tc99m-sestamibi myocardial perfusion scintigraphy (MPS) in pre-and postmenopausal women, and to evaluate whether menopause can be considered an independent risk predictor of ischemia in women with multiple risk factors for CAD.MethodsThis study retrospectively assessed 500 MPS of pre- and postmenopausal women with multiple risk factors for CAD. Statistical analysis was performed by using Fisher exact test and univariate and multivariate analysis, a p value ≤ 0.05 being considered significant.ResultsPostmenopausal women represented 55.9% of the sample; 83.3% were hypertensive; 28.9%, diabetic; 32.1%, smokers; 25%, obese; 61.2% had high cholesterol levels; and 34.3% had known CAD. Postmenopausal women were more often hypertensive, diabetic and dyslipidemic, and had lower functional capacity on exercise testing (p = < 0.005). The presence of ischemia on MPS did not significantly differ between the pre- and postmenopausal groups (p = 0.395). The only variable associated with ischemia on MPS was known CAD (p = 0.004).ConclusionThe results suggest that, in women with multiple risk factors for CAD, menopause was not an independent predictor of ischemia on MPS. Those data support the idea that the investigation of ischemia via MPS in women with multiple risk factors for CAD should begin prior to menopause.

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“…Such data are in accordance with those of the literature. Smanio et al 11 , studying the MPS of 104 asymptomatic diabetic women, have reported myocardial ischemia in 34 (32.7%).…”

Section: Discussionmentioning

confidence: 99%