Doença de Chagas: serviço de referência e epidemiologia

Mendonça, Rafael Mota; Rocha, Aymée Medeiros da; Andrade, Maria Sandra; Silva, Aline Beatriz dos Santos

doi:10.5020/18061230.2019.9364

Cited by 2 publications

(4 citation statements)

References 17 publications

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“…In the present study, the indeterminate form was the most prevalent (44.9%). The digestive form, either isolated or associated with heart disease, had a prevalence of 11.8%, which is within the range of the mean prevalence of this clinical form (9%-41%) presented in other studies 12 - 15 , 17 , 19 , 20 , 22 . Regarding the cardiac and cardiodigestive forms, the most common cardiac stage was stage A (44.4%), which, if associated with the indeterminate form, would account for 65.8% of the cohort, with normal left ventricular systolic function on the ECG indicating patients with long-term benign prognoses.…”

Section: Discussionsupporting

confidence: 82%

“…Field studies performed between 1960 and the early 2000s reported a progressive increase in the mean age of patients with chronic CD over time, from less than 25 to 45 years 31 - 33 . Studies on the clinical epidemiological profile of patients with chronic CD in urban centers reported that the mean age showed the same increasing trend in the last decades, ranging from 37.7 to 67.5 years 12 , 13 , 15 , 20 - 22 . Studies conducted in nonendemic regions of the Northern Hemisphere, where patients migrated from South America, especially Bolivia and Central America, reported younger patients with chronic CD with a mean age ranging from 28.5 to 47 years 16 - 18 , 34 - 37 , reflecting the lack of CD vectorial transmission control in their countries of origin and that CD vectorial transmission remained active in rural areas.…”

Section: Discussionmentioning

confidence: 87%

“…Studies on the clinical form of CD conducted in urban areas have shown that the cardiac form predominates, with a prevalence ranging from 56% to 66% 12 - 16 , 22 , 23 Few studies have reported a higher incidence of the indeterminate form, varying between 56% and 81.6% 17 , 20 . These differences in the prevalence of clinical forms are attributed to the profile of the healthcare unit.…”

Section: Discussionmentioning

confidence: 99%

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Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Hasslocher‐Moreno

Saraiva

Brasil

et al. 2021

Rev. Soc. Bras. Med. Trop.

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INTRODUCTION We aimed to describe the sociodemographic, epidemiological, and clinical characteristics of patients with chronic Chagas disease (CD) at an infectious disease referral center. Changes in patient profiles over time were also evaluated. METHODS This retrospective study included patients with CD from November 1986-December 2019. All patients underwent an evaluation protocol that included sociodemographic profile; epidemiological history; anamnesis; and physical, cardiologic, and digestive examinations. Trend differences for each 5-year period from 1986 to 2019 were tested using a nonparametric trend test for continuous and generalized linear models with binomial distribution for categorical variables. RESULTS A total of 2,168 patients (52.2% women) were included, with a mean age of 47.8 years old. White patients with low levels of education predominated. The reported transmission mode was vectorial in 90.2% of cases. The majority came from areas with a high prevalence (52.2%) and morbidity (67.8%) of CD. The most common clinical presentation was the indeterminate form (44.9%). The number of patients referred gradually decreased and the age at admission increased during the study period, as did the patients’ levels of education. CONCLUSIONS The clinical profile of CD is characterized by a predominance of the indeterminate form of the disease. Regarding the patients who were followed up at the referral center, there was a progressive increase in the mean age and a concomitant decrease in the number of new patients. This reflects the successful control of vector and transfusion transmission in Brazil as well as the aging population of patients with CD.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

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Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Hasslocher‐Moreno

Saraiva

Brasil

et al. 2021

Rev. Soc. Bras. Med. Trop.

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“…Neste estudo, outra questão a ser considerada foi o relato dos entrevistados sobre dificuldade financeira para dar continuidade ao tratamento, visto que o CRDT ficava localizado na capital do Amapá e parte deles residia em outro munícipio ou estado. Sob esta ótica, as doenças negligenciadas refletem a dura realidade vivenciada pelas populações mais carentes, marcada pela baixa cobertura de ações preventivas, precariedade na qualidade e no acesso aos serviços de saúde, e menores chances de receber tratamentos essenciais 28 .…”

Section: Itinerário Em Busca Do Tratamento E Controle Da Doençaunclassified

Doença de Chagas: itinerário terapêutico de crianças e adolescentes em um município da Amazônia

Rocha,

Pantoja,

Mata

et al. 2023

Rev. APS

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No Brasil, a assistência em tempo oportuno aos indivíduos convivendo com Doença de Chagas ainda é um desafio à saúde pública. Objetivou-se analisar o itinerário terapêutico de crianças e adolescentes portadores de Doença de Chagas na busca de atenção e cuidado com a saúde. Adotada a abordagem qualitativa, descritiva, exploratória. Pesquisa de campo realizada com familiares de crianças/adolescentes convivendo com Doença de Chagas no Centro de Referência em Doenças Tropicais (CRDT) em Macapá, AP. Análise de conteúdo subsidiou a identificação de três categorias analíticas: o diagnóstico como desafio inicial do itinerário terapêutico; o Itinerário em busca do tratamento e controle da doença; fragilidades e potencialidades dos serviços de atenção à saúde. Os resultados apontaram que a oferta dos serviços voltados para o diagnóstico da doença ainda está centrada na atenção especializada. Portanto, o itinerário terapêutico de crianças e adolescentes portadores de Doença de Chagas em busca do tratamento e controle da doença é marcado por desafios que envolvem o diagnóstico em tempo oportuno, o que pode repercutir em tratamentos equivocados. A principal fragilidade identificada estava relacionada aos serviços de saúde, pois a atenção primária não está preparada para a identificação da doença, tão pouco a média e alta complexidade estão qualificadas para uma assistência resolutiva. Quanto às potencialidades, estão relacionadas ao sistema de cuidado e atenção à saúde.

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Doença de Chagas: serviço de referência e epidemiologia

Cited by 2 publications

References 17 publications

Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Temporal changes in the clinical-epidemiological profile of patients with Chagas disease at a referral center in Brazil

Doença de Chagas: itinerário terapêutico de crianças e adolescentes em um município da Amazônia

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