Does age affect outcome with breast cancer?

Jackson, E.; Gondara, Lovedeep; Speers, Caroline; Diocee, Rekha M.; Nichol, Alan; Lohrisch, Caroline A.; Gelmon, Karen A.

doi:10.1016/j.breast.2023.06.001

Cited by 10 publications

(3 citation statements)

References 25 publications

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“…The incidence of HER2-positive (HER2+) breast cancer decreases with advancing age yet impacts a substantial proportion of patients diagnosed with breast cancer aged 70 or older, affecting approximately 11% of individuals in this age group [77]. Standard of care first-line treatment for HER2+ ABC was established in the pivotal CLEOPATRA trial publication.…”

Section: Advanced Her2-positive Breast Cancermentioning

confidence: 99%

“…TNBC disease biology is heterogenous, and so too can be the affected patients with regards to age, comorbidities, frailty, and social supports. Although more common amongst younger women, the incidence of TNBC among older adults remains significant, making up almost 10% of all breast cancers diagnosed in those over age 70 [77,92].…”

Section: Advanced Triple-negative Breast Cancermentioning

confidence: 99%

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Key Considerations for the Treatment of Advanced Breast Cancer in Older Adults: An Expert Consensus of the Canadian Treatment Landscape

Jackson,

Curry,

Mariano

et al. 2023

Current Oncology

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The prevalence of breast cancer amongst older adults in Canada is increasing. This patient population faces unique challenges in the management of breast cancer, as older adults often have distinct biological, psychosocial, and treatment-related considerations. This paper presents an expert consensus of the Canadian treatment landscape, focusing on key considerations for optimizing selection of systemic therapy for advanced breast cancer in older adults. This paper aims to provide evidence-based recommendations and practical guidance for healthcare professionals involved in the care of older adults with breast cancer. By recognizing and addressing the specific needs of older adults, healthcare providers can optimize treatment outcomes and improve the overall quality of care for this population.

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Section: Advanced Her2-positive Breast Cancermentioning

confidence: 99%

Section: Advanced Triple-negative Breast Cancermentioning

confidence: 99%

Key Considerations for the Treatment of Advanced Breast Cancer in Older Adults: An Expert Consensus of the Canadian Treatment Landscape

Jackson,

Curry,

Mariano

et al. 2023

Current Oncology

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“…The incidence of breast cancer increases with age and is highest among women aged 50 years and older. The mortality and morbidity rates for breast cancer also increase with age, with the highest rates observed among women over 70 years old (1).…”

Section: Introductionmentioning

confidence: 99%

The relationship between age and mortality and morbidity of patients diagnosed with breast cancer: a retrospective clinical study

DAL,

TEMİZ

2023

Interdisciplinary Medical Journal

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Objective: Breast cancer, the most common malignancy among women, is a universally challenging health problem. It is a known fact that the incidence of breast cancer increases with age. In addition, mortality and morbidity increase with age. For now, it does not seem possible to reduce the incidence of breast cancer but it is possible to limit deaths caused by it. Patients are encouraged to get early diagnosis and age-appropriate screening tests. Because regular screening and early diagnosis are very important in improving breast cancer outcomes. Factors such as age, hormonal status and genetics are associated with the incidence of breast cancer. In this study, we aimed to contribute to the literature by examining age-related mortality and morbidity of breast cancer. Method: This study was carried out at a University Hospital. The sample consisted of 214 women between 01.09.2018/01.09.2022 diagnosed with breast cancer, aged 30 to 80 years. Results: The mean age of women was 51.9 ± 7.6 years, with 52.8% being

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Current approaches to the pharmacological management of metastatic breast cancer in older women

Carmona-Gonzalez,

Kumar,

Menjak

2024

Expert Opinion on Pharmacotherapy

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Does age affect outcome with breast cancer?

Cited by 10 publications

References 25 publications

Key Considerations for the Treatment of Advanced Breast Cancer in Older Adults: An Expert Consensus of the Canadian Treatment Landscape

Key Considerations for the Treatment of Advanced Breast Cancer in Older Adults: An Expert Consensus of the Canadian Treatment Landscape

The relationship between age and mortality and morbidity of patients diagnosed with breast cancer: a retrospective clinical study

Current approaches to the pharmacological management of metastatic breast cancer in older women

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