Does allergic rhinitis exist in infancy? Findings from the PARIS birth cohort

Herr, Marie; Clarisse, Bénédicte; Nikasinovic, Lydia; Foucault, Christophe; Marec, A.; Giordanella, Jean-Pierre; Just, Jocelyne; Momas, Isabelle

doi:10.1111/j.1398-9995.2010.02467.x

Cited by 48 publications

(47 citation statements)

References 37 publications

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“…Unlike the prevalence of atopic dermatitis, the prevalence of allergic rhinitis-like symptoms did not differ among phenotypes, probably because this disorder is a challenge to diagnosis in infants. 39 Risk factors associated with the identified phenotypes Differences in patterns of risk for each phenotype helped us to solve 2 challenges to clustering methods. 40 First, these differences supported the validity of the classification, and second, they made it possible to formulate hypotheses about the cause of phenotypes.…”

Section: Respiratory and Allergic Phenotypesmentioning

confidence: 99%

Risk factors and characteristics of respiratory and allergic phenotypes in early childhood

Herr

Just

Nikasinovic

et al. 2012

Journal of Allergy and Clinical Immunology

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Section: Respiratory and Allergic Phenotypesmentioning

confidence: 99%

Risk factors and characteristics of respiratory and allergic phenotypes in early childhood

Herr

Just

Nikasinovic

et al. 2012

Journal of Allergy and Clinical Immunology

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“…This question assumes that the respondent can correctly identify a cold or 'flu', for example, some children may only have significant symptoms with a combination of both allergic inflammation and a coexisting viral infection. This is a particularly issue in the preschool age (18). Furthermore, ISAAC uses the presence of coexisting itchy eyes to identify allergic rhinitis although this is probably more relevant for pollen-induced rather than rhinitis driven by perennial allergens such as house dust mite.…”

Section: Prevalence and Epidemiologymentioning

confidence: 99%

Paediatric rhinitis: position paper of the European Academy of Allergy and Clinical Immunology

Roberts

Xatzipsalti

Borrego

et al. 2013

Allergy

317

248

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Rhinitis is a common problem in childhood and adolescence and impacts negatively on physical, social and psychological well-being. This position paper, prepared by the European Academy of Allergy and Clinical Immunology Taskforce on Rhinitis in Children, aims to provide evidence-based recommendations for the diagnosis and therapy of paediatric rhinitis. Rhinitis is characterized by at least two nasal symptoms: rhinorrhoea, blockage, sneezing or itching.

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“…In a report from the pollution and asthma risk: an Infant Study (PARIS), 9.1% of the 1859 toddlers in the study cohort reported allergic rhinitis-like symptoms at age 18 months. 5 Though symptoms can develop at younger age in our study we included only children above the age of six years. In this group there were more boys than girls with M: F ratio of 3:2.…”

Section: Discussionmentioning

confidence: 99%

Clinical profile and skin prick test analysis in children with allergic rhinitis of North Kerala, India

Shyna

Kumari

Krishnan

et al. 2018

Int J Contemp Pediatr

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Background: Allergic rhinitis (AR) is increasing in prevalence among children globally and in India. Allergens are factors which trigger allergic rhinitis. Skin prick test (SPT) is a rapid, sensitive and cost effective test to detect IgE- mediated allergic diseases. Identification of common aeroallergens in an area is necessary, in order to educate the patient on what allergens to avoid and also help find the best formulation of allergen immunotherapy for effective AR treatment. This study was done to find the clinical profile and skin sensitivity to common allergens by skin prick test in children with allergic rhinitis between six and fifteen years.Methods: This cross-sectional study was conducted for a period of one year from January 2016 to December 2016. All children between 6 to 15 years with allergic rhinitis were included in the study. Skin prick test was done with seven most common allergens.Results: A total of 60 children with allergic rhinitis were studied and 42 patients (70%) tested positive for SPT. The major symptoms were persistent sneezing (68%), nasal itching (33%), rhinorrhea (85%) and nasal congestion (42%). The proportion of sneezers-runners was higher than blockers (64% versus 36). We tested seven common allergens and house dust mite allergen yielded the highest number of positive responses (33%) followed by cockroach (25%), alternaria (16.66%), parthenium (10%), cat dander (8.35%), sorghum (5%) and dog dander (5%). Among patients with SPT positivity; eight were positive to one allergen, thirteen were positive to two allergens, sixteen to three allergens and five to four allergens.Conclusions: Allergic Rhinitis with a number of allergic co morbidities has a significant impact on the quality of life and scholastic performance in children. Skin prick test which is a standardized, most rapid, sensitive and cost-effective test to detect IgE-mediated allergic diseases is helpful in identifying the common allergens. House dust mite is the commonest allergen tested positive in our study in children.

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Does allergic rhinitis exist in infancy? Findings from the PARIS birth cohort

Abstract: These results support the hypothesis that AR could begin as early as 18 months of life. Suspicion of AR should be reinforced in infants with parental history of AR or biological evidence of atopy, particularly blood eosinophilia and sensitization to inhalant allergens.

Cited by 48 publications

References 37 publications

Risk factors and characteristics of respiratory and allergic phenotypes in early childhood

Risk factors and characteristics of respiratory and allergic phenotypes in early childhood

Paediatric rhinitis: position paper of the European Academy of Allergy and Clinical Immunology

Clinical profile and skin prick test analysis in children with allergic rhinitis of North Kerala, India

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