Does Back Pain Go on Holiday in the Summer?

Roggio, Federico; Musumeci, Giuseppe

doi:10.3390/jfmk7040075

Cited by 1 publication

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These encompassed a broad spectrum, including not only sociodemographic factors, lifestyle factors, body mass index (BMI), biomarkers, diseases and health-related factors, but also vitamin D-specific considerations such as the geographic latitude of the assessment center and seasonality (i.e., the calendar month of attending assessment centers and blood draw) [ 26 ]. Adherence to a healthy lifestyle and the season of assessment are also relevant for LBP and are crucial aspects to adjust for [ 15 , 27 , 28 , 29 ]. The covariates included in the final full models were selected from these determinants of vitamin D deficiency or vitamin D supplement use, along with two additional factors specific to LBP: a history of other musculoskeletal diseases before baseline enrollment (ICD-10: M00-M53, M55-M99) and injuries to the abdomen, lower back, lumbar spine, and pelvis prior to baseline (ICD-10: S30-S39) from primary care data [ 15 ].…”

Section: Methodsmentioning

confidence: 99%

Serum 25-Hydroxyvitamin D Status and Vitamin D Supplements Use Are Not Associated with Low Back Pain in the Large UK Biobank Cohort

Sha,

Chen,

Brenner

et al. 2024

Nutrients

View full text Add to dashboard Cite

Longitudinal studies assessing the association of vitamin D deficiency, defined by serum 25-hydroxyvitamin D levels < 30 nmol/L, and vitamin D supplement (VDS) use with low back pain (LBP) are sparse. This investigation assessed the cross-sectional and longitudinal association of vitamin D status and VDS use with LBP among 135,934 participants from the UK Biobank cohort. Approximately 21.6% of the participants had vitamin D deficiency, while only 4% regularly took VDS. In the month before study enrollment, 3.8% of the population reported experiencing LBP. An additional 3.3% of the population were diagnosed with LBP by their general practitioners for the first time during a median follow-up of 8.5 years. Vitamin D deficiency and VDS use were cross-sectionally associated with LBP in age- and sex-adjusted models, but these associations were not evident in comprehensively adjusted models. In longitudinal analyses, both vitamin D deficiency and VDS use were not associated with LBP in any model after correction for multiple testing. In conclusion, not unexpectedly due to the fact that LBP is multifactorial, our findings provide no evidence for the role of the vitamin D status in the etiology of LBP.

show abstract