Does baseline leisure-time physical activity level predict future depressive symptoms or physical activity among depressive patients? Findings from a Finnish five-year cohort study

Abstract

Objectives: The aims of this study were to investigate whether baseline leisure-time physical activity (LTPA) is associated with future recovery from depression among patients with a depression diagnosis and whether baseline LTPA is associated with total physical activity after five years of follow-up. Methods: A total of 258 patients aged 35 years with clinically confirmed depression at baseline participated. The study was conducted between 2008 and 2016 in municipalities within the Central Finland Hospital District. Depressive symptoms (DS) were determined with the Beck Depression Inventory (BDI) with a cutoff score 10, and depression diagnoses were confirmed by the Mini-International Neuropsychiatric Interview (MINI). Blood pressure and anthropometric parameters were measured and blood samples for glucose and lipid determinations were drawn at baseline. LTPA, physical activity, and other social and clinical factors were captured by standard self-administered questionnaires at baseline and the five-year follow-up point. Results: Of the 258 patients, 76 (29%) had DS at follow-up. Adjusted odds ratio (OR) for future DS was 1.43 (confidence interval [CI] 0.69-2.95) for participants with moderate LTPA and 0.92 (CI 0.42-2.00) for participants with high LTPA, compared with low LTPA at baseline. Higher baseline LTPA levels were associated with higher total physical activity in the future (b¼0.14 [95% CI: 0.02-0.26] for linearity ¼ 0.024). Conclusion: Baseline LTPA did not affect the five-year prognosis of depression among depressed patients in a Finnish adult population. Because the baseline LTPA level predicted the future total physical activity, it could be included as a part of the overall health management and treatment of depression in clinical practices.

Relationship between leisure-time physical activity and depressive symptoms under different levels of dietary inflammatory index

“…There is abundant evidence that the antidepressant effects could emerge with non-medical intervention represented by leisure-time physical activity (LPA) in teenagers' ( 9 – 11 ), middle-aged ( 12 ) and elder ( 13 – 15 ) groups. A recent meta-analysis, which included 49 unique prospective cohort studies and 266,939 participants, found that people with high levels of physical activity had lower odds of developing depression compared with low levels (adjusted OR = 0.83, 95% CI: 0.79 ~ 0.88; I 2 = 0.00) ( 16 ).…”