Does chronic use of amphetamine-type stimulants impair interference control? – A meta-analysis

Opitz, Antje; Petasch, Miriam-Sophie; Klappauf, Regine; Kirschgens, Josephine; Hinz, Julian; Dittmann, Lena; Dathe, Anthea S; Quednow, Boris B.; Beste, Christian; Stock, Ann‐Kathrin

doi:10.1016/j.neubiorev.2022.105020

Cited by 5 publications

(4 citation statements)

References 238 publications

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“…48% of participants (47) applied to OTC at first month, 22.4% of participants (22) applied to OTC at second month, 18.4% of participants (18) applied to OTC at third month, 9.2% of participants (9) applied to OTC at sixth month. Mean ratio of methamphetamine-negative urine test results was 17.7 ± 29.8.…”

Section: Substance Usementioning

confidence: 99%

“…Although emerging evidence in the literature with cognitive impairments shows the association with lower treatment retention, no study investigated the aforementioned domains among the same METH users sample. [18][19][20] For these reasons, we proposed to carry out a study to understand the effect and interaction of cognitive functioning, severity of psychotic symptoms, demographic factors and medications with a 6-month follow up among METH users which were followed in the outpatient treatment clinic (OTC). Recognizing the predictors of less frequent METH use and its interaction with medication adherence may be helpful for patients and practitioners to create more effective treatment process.…”

Section: Introductionmentioning

confidence: 99%

“… 17 These higher-level cognitive processes are closely associated with impulsive behaviors, compulsive drug use and craving therefore cognitive impairments may increase the risk of relapse among individuals with METH use. 18 Among the core executive functions inhibition (especially behavioral and cognitive) and related attention processes plays an important role in abstinence. Dealing with drug related cues and craving are also crucial aspects of drug-free lives.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A 6-Month Follow-Up Study: Cognitive Impairment May Predict More Frequent Use of Methamphetamine

Karabulut¹

2023

Subst�Abuse

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Objectives: Methamphetamine (METH) use has been associated with impairments in a variety of cognitive functions. In this study, it was aimed to assess the relation between cognitive measures and frequency of METH use. Methods: Ninety-eight participants with methamphetamine use disorder were assessed with Wisconsin Card Sorting Test (WCST), Victoria-Stroop Word Color Test (SWCT), Trail Making Test (TMT) A and B. Participants were followed up during 6-month period with multiple urine toxicology tests (at baseline, month 1, month 2, month 3 and month 6). Results: Participants who had their prescriptions regularly were more likely to have higher rates of METH-negative urine results ( P = .003). Participants who had more correct numbers, completed more categories and had more conceptual level responses on WCST were more likely to use lower frequency of METH (OR = 0.006, P < .01; OR = 0.171, P < .001; OR = 0.024, P < .001; respectively). The higher error numbers and perseverative error rates on WCST were associated with more frequent METH use (OR = 0.023, P < .001; OR = 0.076, P < .001). Interference factor on SWCT was related with lower frequency of METH use whereas color naming factor on SWCT was related with higher rates of urine results (OR = 0.012, P < .001; OR = 3.628, P < .001; respectively). Higher TMT B-A score was related with more frequent METH use, although the significance disappeared after adjustment (OR = 0.002, P < .001). Having psychotic symptoms predicted less frequent use, but after adjustment for other significant variables, there was no significance. Conclusion: Lower frequency of METH use in the follow-up could be predicted by neurocognitive assessments. Deficits in executive functions, attention, set-shifting and mental flexibility seems to be the most effected domains and this effect may be independent from the severity of psychotic symptoms.

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Section: Substance Usementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A 6-Month Follow-Up Study: Cognitive Impairment May Predict More Frequent Use of Methamphetamine

Karabulut¹

2023

Subst�Abuse

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Validity of the brief executive-function assessment tool in an outpatient substance use disorder setting

Brooks,

Berry,

Shores

et al. 2024

Applied Neuropsychology: Adult

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Patterns and Characteristics of Amphetamine-type Stimulant Use in a North-eastern State of India: A Cross-sectional Study

Rao,

Ganesh,

Kishore

et al. 2024

Indian Journal of Psychological Medicine

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Background: South Asia generally reports low levels of amphetamine-type stimulant (ATS) use, with few studies on the pattern of ATS use. We assessed the pattern of ATS use and associated high-risk behavior in Manipur, a north-eastern state of India. Methods: 209 adult male ATS users (mean age 28.8 years) from three districts of Manipur were interviewed. Data were collected on the patterns of high-risk behavior with ATS use, health consequences, and help-seeking. The severity of use with various substances was assessed using the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST). Depression and anxiety were assessed by the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) scale, respectively. Results: The mean duration of ATS use was 3.7 years (SD 2.3). The majority used ATS almost daily (88%) and depended on ATS (77%). Methamphetamine (99.5%) was the most used ATS orally. Around 87% also suffered from opioid dependence. About 76% injected drugs, most commonly heroin. Almost three-fourths (78%) used ATS before their sexual intercourse, 31% of whom did not use condoms. Most reported physical problems with ATS and had above-cut-off scores on PHQ-9 and GAD-7. The majority (95%) reported that they could procure ATS easily. Also, the majority (93%) had thought of quitting ATS use. Discussion: Most ATS users start using ATS at a young age and have comorbid other drug use, including heroin. ATS use is associated with various physical and psychological problems. Focusing on ATS use in India and developing strategies to address this problem is essential.

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Does chronic use of amphetamine-type stimulants impair interference control? – A meta-analysis

Cited by 5 publications

References 238 publications

A 6-Month Follow-Up Study: Cognitive Impairment May Predict More Frequent Use of Methamphetamine

A 6-Month Follow-Up Study: Cognitive Impairment May Predict More Frequent Use of Methamphetamine

Validity of the brief executive-function assessment tool in an outpatient substance use disorder setting

Patterns and Characteristics of Amphetamine-type Stimulant Use in a North-eastern State of India: A Cross-sectional Study

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