Does cognition predict community function only in schizophrenia?: A study of schizophrenia patients, bipolar affective disorder patients, and community control subjects

Laes, Jo An R.; Sponheim, Scott R.

doi:10.1016/j.schres.2005.11.023

Cited by 80 publications

(49 citation statements)

References 45 publications

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“…Executive functions, which comprise of a number of abilities, have also been connected with social function. Previous results suggest that not all of these abilities are related to social function as a link between executive functions and social function appears to only emerge when some tests are used (Stroop task, word fluency and the trail making test) but not others (Wisconsin Card Sorting Test, Theory of Mind) (Martinez-Aran et al, 2004a;Olley et al, 2005;Laes and Sponheim, 2006;Torrent et al, 2006;Cusi et al, 2012). Our findings failed to show any link, although BD participants showed a poorer performance than the control participants in most tasks.…”

Section: Discussioncontrasting

confidence: 89%

“…Previous studies focusing on cognitive abilities in relationship to social function frequently identified verbal memory abilities as associated with functioning both when clinician administered and with self-report measures (Martinez-Aran et al, 2004b;Laes and Sponheim, 2006;Bonnín et al, 2014). When using more specific measures of functioning such as occupational measures this link has not always been reported (Torrent et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

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Influence of personality and neuropsychological ability on social functioning and self-management in bipolar disorder

Vierck

Joyce

2015

Psychiatry Research

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Section: Discussioncontrasting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Influence of personality and neuropsychological ability on social functioning and self-management in bipolar disorder

Vierck

Joyce

2015

Psychiatry Research

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“…Nearly 40% of early-onset patients showed cognitive impairment in later life, and 27% also showed impaired functional outcome using the GAF [113]. Other recent reports have suggested that frontal executive impairments may also be related to low psychosocial functioning [114,115,116,117]. To date, there are only two longitudinal studies focused on cognitive functioning as predictor of functioning.…”

Section: Resultsmentioning

confidence: 99%

Functioning and Disability in Bipolar Disorder: An Extensive Review

Sanchez-Moreno

Martínez-Àran

Tabarés‐Seisdedos

et al. 2009

Psychother Psychosom

367

282

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Background: Bipolar disorder has generally been regarded as having a better functional outcome than schizophrenia. However, studies have suggested low functioning in bipolar patients even when they are in clinical remission. Our aim was to determine the degree of functioning and disability in bipolar patients. Secondly, we reviewed factors potentially associated with the low functioning of bipolar patients. Method: The authors conducted an extensive Medline and Pubmed search of the published literature from 1980 up to December 2007, using a variety of search terms to find relevant articles. Bibliographies of retrieved papers were further analysed for publications of interest. Articles that reported clinically significant findings on functioning and disability, and research reports were reviewed in detail. Results: From these articles, we determined that bipolar disorder is associated with significant impairment in work, family and social life, beyond the acute phases of the illness. The aspects that appear to increase the risk of low functioning and disability in bipolar patients are mainly subsyndromal symptoms and neurocognitive impairment, among others. Conclusions: Suitable pharmacological and psychological interventions may improve the level of functioning and reduce the disability in bipolar patients. Potential targets to be considered for intervention should be residual symptoms, comorbid conditions and neurocognitive deficits. Further research is required to better identify the factors that best predict functioning in bipolar patients.

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“…However, only a minority (43%) had achieved functional recovery. The dysfunction experienced by BD patients appears to be related to cognitive abnormalities that include verbal memory (Laes and Sponheim 2006), impaired decision-making, and problem-solving (Laes and Sponheim 2006;Rubinsztein et al 2006), and impaired affective recognition and processing (Bozikas et al 2006;Malhi et al 2005). It is imperative that we understand what underlies these cognitive abnormalities so that we may address them clinically and improve outcome.…”

Section: Discussionmentioning

confidence: 99%

Event-related Potential Study of the Effects of Emotional Facial Expressions on Task Performance in Euthymic Bipolar Patients

Sokhadze

Tasman

Tamas

et al. 2010

Appl Psychophysiol Biofeedback

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There appears to be a significant disconnect between symptomatic and functional recovery in bipolar disorder (BD). Some evidence points to interepisode cognitive dysfunction. We tested the hypothesis that some of this dysfunction was related to emotional reactivity in euthymic bipolar subjects may effect cognitive processing. A modification of emotional gender categorization oddball task was used. The target was gender (probability 25%) of faces with negative, positive, and neutral emotional expression. The experiment had 720 trials (3 blocks × 240 trials each). Each stimulus was presented for 150 ms, and the EEG/ERP responses were recorded for 1,000 ms. The inter-trial interval was varied in 1,100-1,500 ms range to avoid expectancy effects. Task took about 35 min to complete. There were 9 BD and 9 control subjects matched for age and gender. Reaction time (RT) was globally slower in BD subjects. The centro-parietal amplitudes at N170 and N200, and P200 and P300 were generally smaller in the BD group compared to controls. Latency was shorter to neutral and negative targets in BD. Frontal P200 amplitude was higher to emotional negative facial non-targets in BD subjects. The frontal N200 in response to positive facial emotion was less negative in BD subjects. The frontal P300 of BD subjects was lower to emotionally neutral targets. ERP responses to facial emotion in BD subjects varied significantly from normal controls. These variations are consistent with the common depressive symptomology seen in long term studies of bipolar subjects.

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Does cognition predict community function only in schizophrenia?: A study of schizophrenia patients, bipolar affective disorder patients, and community control subjects

Cited by 80 publications

References 45 publications

Influence of personality and neuropsychological ability on social functioning and self-management in bipolar disorder

Influence of personality and neuropsychological ability on social functioning and self-management in bipolar disorder

Functioning and Disability in Bipolar Disorder: An Extensive Review

Event-related Potential Study of the Effects of Emotional Facial Expressions on Task Performance in Euthymic Bipolar Patients

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