Does Deficiency of Vitamin D Increase New Onset Atrial Fibrillation after Coronary Artery Bypass Grafting Surgery?

Emren, Sadık Volkan; Aldemir, Mustafa; Ada, Fatih

doi:10.1532/hsf.1531

Cited by 19 publications

(24 citation statements)

References 23 publications

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“…Low vitamin D levels are associated with HF and atrial fibrillations (AF) in HF patients [92]. Low levels of vitamin D are significantly associated with more extensive left atrial fibrosis in patients with lone paroxysmal AF as well as with recurrence of AF after cryoablation [93] and post coronary-artery bypass graft surgery [94]. These results suggest that low vitamin D levels are associated with increased incidence of AF.…”

Section: Cardiac Diseasesmentioning

confidence: 99%

Role of Vitamin D in Cardiovascular Diseases

Rai

Agrawal

2017

Endocrinology and Metabolism Clinics of North America

122

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Vitamin D is critical in mineral homeostasis and skeletal health, and plays regulatory role in non-skeletal tissues. Vitamin D deficiency is associated with chronic inflammatory diseases, including diabetes and obesity both being strong risk factors for cardiovascular diseases (CVD). CVD, including coronary artery disease, myocardial infarction, hypertrophy, cardiomyopathy, cardiac fibrosis, heart failure, aneurysm, peripheral arterial disease, hypertension, and atherosclerosis, are major causes of morbidity and mortality worldwide. The association of these diseases with vitamin D deficiency and improvement with vitamin D supplementation suggest its therapeutic benefit. Here, we critically review the recent findings on the association of vitamin D deficiency and CVD.

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Section: Cardiac Diseasesmentioning

confidence: 99%

Role of Vitamin D in Cardiovascular Diseases

Rai

Agrawal

2017

Endocrinology and Metabolism Clinics of North America

122

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“…There are many publications in the literature on low vitamin D levels and postoperative AF 3,4 . In recent years, there are many publications in the literature regarding the relationship between vitamin D deficiency and postoperative AF development.…”

Section: Introductionmentioning

confidence: 99%

Is there a seasonal feature of new onset atrial fibrillation after coronary artery bypass graft surgery?

Ada

Polat

2019

Cumhuriyet Medical Journal

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Atrial fibrillation (AF) is seen as very common after cardiac surgery. Postoperative AF occurrence increases mortality and morbidity. Deterioration of clinical condition of the patients results prolongation of hospital stay and increases economic burden. Many risk factors that have an impact on the development of postoperative AF are known. Low vitamin D level has been added to these factors in recent years. Blood serum levels of vitamin D is varied seasonally. Therefore, these factors can be expected to have a seasonal effect on development of postoperative AF. The aim of this study is to investigate the presence of annual features of postoperative AF. Method: This study is a retrospective analysis of patients who developed atrial fibrillation after coronary artery bypass graft surgery in the

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“…POAF incidence was significantly higher in patients with vitD deficiency or insufficiency than in patients with normal vitD level in previous studies [2,3] . In our previous study, although there was a significant negative correlation between vitD and left atrial diameter, vitD level was not an independent predictor for POAF [7] .…”

Section: Discussionmentioning

confidence: 64%

Preventive Effect of Preoperative Vitamin D Supplementation on Postoperative Atrial Fibrillation

Cerit¹,

Özçem²,

Cerit³

et al. 2018

Braz J Cardiovasc Surg

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ObjectiveTo assess the relationship between preoperative vitamin D (vitD) supplementation and the development of postoperative atrial fibrillation (POAF).MethodsThe study group consisted of 328 consecutive patients. The ınfluence of preoperative vitD supplementation on POAF was reviewed in 136 patients who underwent coronary artery bypass graft surgery with vitD insufficiency (n=80) and vitD deficiency (n=56). Patients were assigned to receive either oral vitD (50.000 U) (treatment group, n=68) or not (control group, n=68) 48 hours before surgery. Patients were followed up during hospitalisation process with respect to POAF.ResultsThere was no significant difference between treatment and control groups with regards to age, gender, diabetes mellitus, smoking history, chronic obstructive pulmonary disease, left atrial diameter, and biochemical parameters. Also, there was no significant difference between these groups with regards to mean vitD level on both insufficiency and deficiency patients (24.6±3.7 vs. 24.9±3.9 ng/ml P=0.837, 11.4±4.9 vs. 10.9±5.2 ng/ml P=0.681, respectively). Although the occurrence of POAF was not significantly different among treatment and control groups in patients with vitD insufficiency (31% vs. 33% P=0.538), there was a significant difference between the two groups regarding to POAF in patients with vitD deficiency (18% vs. 29% P=0.02).ConclusionAlthough preoperative vitD supplementation was not found to be associated with prevention of POAF in patients with vitD insufficiency, it was found to be strongly associated with prevention of POAF in those with vitD deficiency.

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Does Deficiency of Vitamin D Increase New Onset Atrial Fibrillation after Coronary Artery Bypass Grafting Surgery?

Abstract: This study has shown that deficiency of vitamin D is associated with new onset AF post-CABG surgery.

Cited by 19 publications

References 23 publications

Role of Vitamin D in Cardiovascular Diseases

Role of Vitamin D in Cardiovascular Diseases

Is there a seasonal feature of new onset atrial fibrillation after coronary artery bypass graft surgery?

Preventive Effect of Preoperative Vitamin D Supplementation on Postoperative Atrial Fibrillation

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