2022
DOI: 10.3390/jcm11133893
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Does Demineralized Bone Matrix Affect the Nonunion Rate in Arthroscopic Ankle Arthrodesis?

Abstract: Demineralized bone matrix (DBM) has been shown to have positive effects on union rates in many orthopedic subspecialties; however, minimal evidence exists about bone graft substitutes in foot and ankle surgery. The purpose of this study is to compare nonunion rates in arthroscopic ankle arthrodesis in patients receiving DBM with those without. We hypothesized DBM to be associated with a decreased risk of nonunion. This retrospective review includes 516 consecutive ankle arthrodesis cases from March 2002 to May… Show more

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Cited by 2 publications
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“…29 The surgical methods used in the included studies in this review and the indications for fusion were variable, and this constitutes a major limitation. 7,23,25,26,32 Posttraumatic osteoarthritis or primary osteoarthritis was likely the most common indication for ankle fusion; however, patients with other diagnosis such as rheumatoid arthritis or Charcot disease were also included in the included studies, but the outcomes were not analyzed by surgical indication. 4,11,[15][16][17]31,32 In the surgical techniques, there was variability in the fixation construct used among the included articles and occasionally among the patients included in the same study population such as plate and screws, screws only, or intramedullary nails and/or combination of the above.…”
Section: Discussionmentioning
confidence: 99%
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“…29 The surgical methods used in the included studies in this review and the indications for fusion were variable, and this constitutes a major limitation. 7,23,25,26,32 Posttraumatic osteoarthritis or primary osteoarthritis was likely the most common indication for ankle fusion; however, patients with other diagnosis such as rheumatoid arthritis or Charcot disease were also included in the included studies, but the outcomes were not analyzed by surgical indication. 4,11,[15][16][17]31,32 In the surgical techniques, there was variability in the fixation construct used among the included articles and occasionally among the patients included in the same study population such as plate and screws, screws only, or intramedullary nails and/or combination of the above.…”
Section: Discussionmentioning
confidence: 99%
“…The interpretation of the outcomes in clinical trials can be challenging given multiple follow-up points and the utilization of functional outcomes scores in combination with the corresponding variable minimal clinically important difference values that have not always be validated for the diagnosis of interest. 32 As an example, most of the reported minimal clinically important difference values for FFI or AOFAS stemmed from study populations undergoing common procedures such as correction of hallux valgus and not necessarily ankle/hindfoot fusion. 33,34 In addition, there was a lack of consistency in the time interval and definition of nonunion versus delayed-union, and the defined benchmark for successful fusion varied greatly, as well as the level of accuracy in the imaging method used to assess fusion (CT versus plain radiograph).…”
Section: Discussionmentioning
confidence: 99%
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