“…Early initiation of treatment in RA assists patients in attaining improved outcomes and drug-free remission by profoundly modifying the pathogenesis of RA. [31][32][33][34] RA patients on early DMARDs show a significantly lower disease progression rate, irrespective of the differences in treatment regimen or disease characteristics. [35][36][37] Studies have also shown that early intervention group had significantly lower radiographic damage at 5 years.…”