Does fasting during Ramadan trigger non-adherence to oral hormonal therapy in breast cancer patients?

Zeeneldin, Ahmed A.; Gaber, Ayman; Taha, Fatma

doi:10.1016/j.jnci.2012.06.003

Cited by 39 publications

(16 citation statements)

References 11 publications

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“…In Egypt (n = 139), adherence to oral hormonal therapy during fasting month (Ramadan) was 94.2% with no significant difference from other months of the year. 45 Still, the non-adherence ratio 7% reported in the present study, is less than reports from other developing countries, such as 23.7% nonadherence in Brazil, 46 %24 in Nigeria, 30 and 36% in South Africa 31 respectively . This is understandable since a non-adherence of 20% is equivalent to missing at least one tablet every 5 days, 43 while in our study only 7% (12/172) missed more than one pill per week during their treatment duration.…”

Section: Discussioncontrasting

confidence: 82%

“…Although, the adherence ratio revealed in this study remains high comparable to developing countries, it is not the first time such a high adherence is reported. In Egypt (n = 139), adherence to oral hormonal therapy during fasting month (Ramadan) was 94.2% with no significant difference from other months of the year 45 . Still, the non‐adherence ratio 7% reported in the present study, is less than reports from other developing countries, such as 23.7% non‐adherence in Brazil, 46 %24 in Nigeria, 30 and 36% in South Africa 31 respectively .…”

Section: Discussioncontrasting

confidence: 64%

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Adherence to endocrine therapy and its relation to disease‐free survival among breast cancer patients visiting an out‐patient clinic at Khartoum Oncology Hospital, Sudan

Mohamed

Elamin

2020

Evaluation Clinical Practice

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Rationale: Adherence to endocrine therapy provides substantial reduction in breast cancer (BC) relapses and improve survival. Hence, non-adherence remains an under reported issue mainly in developing countries. Aims and Objectives: The aim of this study is to evaluate the adherence to endocrine therapy (tamoxifen [TAM] and aromatase inhibitors [AIs]) among BC patients visiting an outpatient clinic (2015-2016) in Khartoum Oncology Hospital, Sudan. Methods: Adherence was assessed using pills count and self-reporting methods. A total of 172 patients were interviewed. Also, records were reviewed for demographic and other cancer characteristics. Results: The patients' mean age at diagnosis was 53 years, with the highest frequency at (41-60) years. Invasive ductal carcinoma 69.2% formed the main pathological diagnosis. T2 tumour size (51.2%) and lymph node involvement (N1) (31.4%) were most evident. Also, the majority of patients were stage III (45.9%) and grade II (48%). The studied women were postmenopausal (49.4%) and premenopausal (47.7%). Regarding hormonal receptors, about 68% were oestrogen (ER)+/progesterone (PR)+ and 23.3% were ER+/PR−. Studying adherence, almost (93%) of the studied group were ≥80% adherent to TAM and AIs. The hormonal therapy persistence mean was 27.2 ± 22.5 months (40-96). While adherence percentage mean was 93.7 ± 13.6% (0%-100%). Also disease-free survival (DFS) mean was 36.3 ± 32.7 months (4-312).

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Section: Discussioncontrasting

confidence: 82%

Section: Discussioncontrasting

confidence: 64%

Adherence to endocrine therapy and its relation to disease‐free survival among breast cancer patients visiting an out‐patient clinic at Khartoum Oncology Hospital, Sudan

Mohamed

Elamin

2020

Evaluation Clinical Practice

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“…A number of studies, the majority of which were done in non-Muslim countries, addressed the communication lapses between clinicians and patients who decide to fast during Ramadan [18][19][20][21][22][23][24][25][26][27]. At times, the topic is never addressed in clinical encounters that occur before or during Ramadan.…”

Section: Introductionmentioning

confidence: 99%

RAMCOM: A qualitative study of clinicians’ viewpoints on a tool for communication with Muslim patients considering fasting during Ramadan

Amin

Abdelmageed

2020

PLoS ONE

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Fasting during the month of Ramadan is a basic pillar of Islam. While patients may be religiously exempted from fasting, literature indicates that the majority decide to fast. Caring for millions of Muslim patients who decide to fast during Ramadan can be challenging for clinicians around the globe. This study proposes a communication tool, RAMCOM, which aims to assist clinicians in communicating with Muslim patients considering fasting during Ramadan. It addresses the following questions: What are the clinicians' preferences for the tool in terms of Content, Format, Style, Length and language? How do clinicians perceive factors that would impact their intentions to sue the tool? What would facilitate the implementation and dissemination of the proposed tool? Methods Semi-structured interviews were conducted with a purposeful sample of clinicians in Egypt (11) and the US (10). Clinicians were purposefully sampled to assure variance in age, gender, time in practice, specialty, and religious background. Directed content analysis was conducted and emerging data were mapped to constructs within the theory of planned behavior. Iterative sampling and analysis continued until saturation was reached. Results In total, 21 clinicians were interviewed. The tool was iteratively revised according to clinicians' comments on format, content, language and usability. Factors contributing to using RAMCOM included perception of tool (need for use, perceived burden of use), perceived norm (perceived patient expectations), and ability to use tool (time, frequency of seeing patients, knowledge of Ramadan and Islam). Practice environment factors that impact the use of RAMCOM include education, early reminders, colored laminated copies, communication training, involvement of support staff, and patient education.

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“…These results corroborate findings of previous work suggesting that a large percentage of Muslim patients with chronic conditions choose to fast even when they have a religious exemption from fasting. [3,6,23,24] This finding highlights the importance of preparing health professionals, including pharmacists, to deal with this issue in Muslim countries as well as non-Muslim countries where Muslim minorities live.…”

Section: Discussion and Conclusion Discussionmentioning

confidence: 96%

Pharmacist–patient communication about medication regimen adjustment during Ramadan

Amin

Chewning

2016

International Journal of Pharmacy Practice

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Does fasting during Ramadan trigger non-adherence to oral hormonal therapy in breast cancer patients?

Abstract: While most of patients receiving OHT for BC are fasting during Ramadan, this does not negatively impact compliance with treatment.

Cited by 39 publications

References 11 publications

Adherence to endocrine therapy and its relation to disease‐free survival among breast cancer patients visiting an out‐patient clinic at Khartoum Oncology Hospital, Sudan

Adherence to endocrine therapy and its relation to disease‐free survival among breast cancer patients visiting an out‐patient clinic at Khartoum Oncology Hospital, Sudan

RAMCOM: A qualitative study of clinicians’ viewpoints on a tool for communication with Muslim patients considering fasting during Ramadan

Pharmacist–patient communication about medication regimen adjustment during Ramadan

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