Does feedback of medication execution using MEMS caps aid adherence to HAART?: the MEMRI study (MEMS as Realistic Intervention)

Davies, Sophia; Asghar, Saima; Cooper, Vanessa; Lange, Alissa A.; Robertson, C; Vrijens, Bernard; White, D. Jean

doi:10.1186/1758-2652-13-s4-p120

Cited by 5 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Examples of providing feedback to patient's included providing patients with graphical display of their adherence, 52 providing adherence performance to clinicians for use in routine patient encounters, 44 and having dedicated sessions apart from clinical patient encounters to discuss adherence performance and devise improvement strategies. 48 …”

Section: Resultsmentioning

confidence: 99%

“…These fell into 3 categories: subjective patient perceptions (4 studies), 22,48,55,58 factors other than EMP that affected adherence (3), 44,52,53 and potential risks of EMP (3). 16,35,45 …”

Section: Resultsmentioning

confidence: 99%

“…55 Additionally, all 3 studies that compared adherence on weekdays to weekends found that adherence was worse on weekends, with one study also finding that evening doses were omitted more frequently than morning doses. 44,52,53 …”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Electronic Medication Packaging Devices and Medication Adherence

Checchi

Huybrechts

Avorn

et al. 2014

JAMA

176

126

View full text Add to dashboard Cite

Importance Medication non-adherence, which has been estimated to affect 28-31% of US patients with hypertension, hyperlipidemia, and diabetes, may be improved by electronic medication packaging (EMP) devices. Objective To investigate whether EMP devices are associated with improved adherence and to identify and describe common features of EMP devices. Evidence Acquisition We systematically reviewed peer-reviewed studies testing the effectiveness of EMP systems in the MEDLINE, EMBASE, PsycINFO, CINAHL, and International Pharmaceutical Abstracts databases from searches conducted to June 13, 2014. We extracted the associations between the interventions and adherence, as well as other key findings. We assessed each study for bias using the Cochrane Handbook for Systematic Reviews of Interventions. We qualitatively assessed features of EMP devices and interventions. Results 37 studies (32 randomized and 5 non-randomized) including 4,326 patients met review criteria: 10 patient-interface-only “simple” interventions and 29 “complex” interventions integrated into the health care system (2 qualified for both categories). Overall, the effect estimates for mean adherence ranged from -2.9 to 34.0% and the effect estimates for the proportion of patients defined as adherent ranged from -8.0 to 49.5%. We identified 5 common EMP characteristics: recording dosing events and storing a record of adherence, audiovisual reminders to cue dosing, digital displays, real-time monitoring, and providing patients with adherence performance feedback. Conclusion and Relevance Many varieties of EMP exist. However, data supporting their use are limited, with variability in the quality of studies testing EMP devices and evidence of reporting bias. Devices that are integrated into the care delivery system and that are designed to record dosing events are most frequently associated with improved adherence. Higher quality evidence is needed to determine the effect, if any, of these low cost interventions on medication nonadherence and to identify their most useful components.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Electronic Medication Packaging Devices and Medication Adherence

Checchi

Huybrechts

Avorn

et al. 2014

JAMA

176

126

View full text Add to dashboard Cite

show abstract

“…Unannounced home visits may get around this problem, but such efforts are clearly expensive and not always welcome. The use of electronic monitoring devices, such as medication event monitoring system (MEMS) pill bottle caps, is also common, but costly . The device records the date and time that the bottle was opened.…”

Section: Definitions and Measurementmentioning

confidence: 99%

Non-adherence to medication in patients with psychotic disorders: epidemiology, contributing factors and management strategies

2013

View full text Add to dashboard Cite

Although non-adherence is common across all branches of medicine, psychotic disorders pose additional challenges that increase its risk. Despite the importance of non-adherence, clinicians generally spend too little time on assessing and addressing adherence attitudes and behaviors. Importantly, how adherence is measured significantly impacts the findings, and the most frequently employed methods of asking patients or judging adherence indirectly based on efficacy or tolerability information have poor validity. Novel technologies are being developed that directly assess adherence and that can also be used to both provide real-time feedback to clinicians and serve as an intervention with patients. Several treatments are available that can positively impact adherence. Among psychosocial interventions, those combining multiple approaches and involving multiple domains seem to be most effective. Although long-acting injectable antipsychotics are theoretically a very powerful tool to assure adherence and signal non-adherence, recent results from randomized controlled trials failed to show superiority compared to oral antipsychotics. These data are in contrast to nationwide cohort studies and mirror-image studies, which arguably include more representative patients receiving long-acting antipsychotics in clinical practice. This disconnect suggests that traditional randomized controlled trials are not necessarily the best way to study interventions that are thought to work via reducing non-adherence. Clearly, non-adherence is likely to remain a major public health problem despite treatment advances. However, increasing knowledge about factors affecting adherence and leveraging novel technologies can enhance its early assessment and adequate management, particularly in patients with psychotic disorders.

show abstract

“…Samples or old medications are also noted to compromise the results obtained using pill counts and pharmacy refill records (Velligan et al, 2010). These electronic monitoring devices; MEMS pill bottle caps, although common, are costly (Davies et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

Measuring Medication Adherence in Patients With Schizophrenia: An Integrative Review

Bright

2017

Archives of Psychiatric Nursing

View full text Add to dashboard Cite

Does feedback of medication execution using MEMS caps aid adherence to HAART?: the MEMRI study (MEMS as Realistic Intervention)

Abstract: 7‐11 November 2010, Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK

Cited by 5 publications

References 0 publications

Electronic Medication Packaging Devices and Medication Adherence

Electronic Medication Packaging Devices and Medication Adherence

Non-adherence to medication in patients with psychotic disorders: epidemiology, contributing factors and management strategies

Measuring Medication Adherence in Patients With Schizophrenia: An Integrative Review

Contact Info

Product

Resources

About