Background: Healthcare structures around the globe are appropriately increasingly curious about heartening the role of subjects in their care and stretch to evolve them. Aim: This study aimed to assess patient empowerment at the National Institute of Diabetes and Endocrinology in the Internal Medicine and Surgery departments. Methods: This was a descriptive study. 400 diabetic patients were included in this study that was conducted at the National Institute of Diabetes and Endocrinology, Cairo. Data were gathered using the self-control questionnaire including the patient enablement instrument, the control preferences scale, and the patient activation measure. Results : Regarding patient activation, 69% of patients had high levels of activation, and only 14 % of them were low,50.5% actively preferred decision-making, 52% of them had low levels of enablement following clinician consultation, and only 20 % were moderate, 54.5% who had low levels of diabetic self-control and only (18.5 %) had high control of diabetes. Conclusion: This study found that almost two-thirds of the sample had a high degree of activation and that slightly more than half preferred to make medical decisions on their own or did so while taking the doctor's advice into account those were active, and slightly more than half of the studied sample were enabled and their score after clinical consultation was low and slightly more than half of the studied patients were low self-control of diabetes.