Does hydration prevent radiocontrast-induced acute renal failure?

2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

“…The basic principle of hydration follows from experimental studies and clinical experience, with isotonic or half-normal saline alone being the historical gold standards. 965,966,[986][987][988] More recently, sodium bicarbonate has been tested as the hydrating solution. Some trials have reported superiority of sodium bicarbonate over saline in preventing CIN.…”

2012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update)

“…The basic principle of hydration follows from experimental studies and clinical experience, with isotonic or half-normal saline alone being the historical gold standards. 164,165,[182][183][184] More recently, sodium bicarbonate has been tested as the hydrating solution. Some trials have reported superiority of sodium bicarbonate over saline in preventing CIN.…”

Contrast induced nephropathy - cardiologist perspective

“…The disadvantages of hydration include its unsuitability for patients with cardiac failure and its limited use in emergency situation resulting from its requirement of fluid administration for several hours before contrast medium exposure. 42 Based on the above evidence, all patients undergoing contrast-related procedure should receive adequate hydration. The most widely accepted protocol is administering 0.45% saline at 1 to 1.5 ml/kg/h beginning 6 -12 h prior to the procedure and continuing for up to 12 h following contrast administration.…”