2017
DOI: 10.1155/2017/8741851
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Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma?

Abstract: Many studies have been done to evaluate the effect of various natural products in controlling asthma symptoms. Virgin coconut oil (VCO) is known to contain active compounds that have beneficial effects on human health and diseases. The objective of this study was to evaluate the effect of VCO inhalation on airway remodelling in a rabbit model of allergic asthma. The effects of VCO inhalation on infiltration of airway inflammatory cells, airway structures, goblet cell hyperplasia, and cell proliferation followi… Show more

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Cited by 9 publications
(5 citation statements)
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“…Coconut oil is known for its numerous beneficial effects including prevention and treatment of Alzheimer disease [ 190 ], supporting bone health and preventing osteoporosis [ 191 ], controlling blood sugar [ 192 ], stress-reducing and antioxidant effects [ 193 ], preventing liver disease [ 194 ], reducing asthma symptoms [ 195 ], improving dental health [ 196 ] and reducing body weight [ 197 ]. On the other hand, there are also opposite or controversial opinions about the effects of coconut oil in the human diet due to high content of saturated FA (90%), which has been positively correlated with the increase of LDL-C [ 198 ].…”
Section: The Effect Of Coconut Oil On Cardiovascular Health and Diseasesmentioning
confidence: 99%
“…Coconut oil is known for its numerous beneficial effects including prevention and treatment of Alzheimer disease [ 190 ], supporting bone health and preventing osteoporosis [ 191 ], controlling blood sugar [ 192 ], stress-reducing and antioxidant effects [ 193 ], preventing liver disease [ 194 ], reducing asthma symptoms [ 195 ], improving dental health [ 196 ] and reducing body weight [ 197 ]. On the other hand, there are also opposite or controversial opinions about the effects of coconut oil in the human diet due to high content of saturated FA (90%), which has been positively correlated with the increase of LDL-C [ 198 ].…”
Section: The Effect Of Coconut Oil On Cardiovascular Health and Diseasesmentioning
confidence: 99%
“…The results indicated the ability of 10% of VCO to prevent the growth of cells and stimulation of cell death (at a concentration of 8.64% and 12.04%) during 72 h incubation. [53] Law et al [54] studied the role of coconut oil supplementation in patients with breast cancer. VCO was consumed twice a day (each time, 10 mL) by the patients in addition to three, four, five, and six cycles of chemotherapy, and the results were compared with the control group.…”
Section: Cancermentioning
confidence: 99%
“…The results indicated the ability of 10% of VCO to prevent the growth of cells and stimulation of cell death (at a concentration of 8.64% and 12.04%) during 72 h incubation. [ 53 ] Law et al. [ 54 ] studied the role of coconut oil supplementation in patients with breast cancer.…”
Section: Health Effectsmentioning
confidence: 99%
“…The impact of virgin coconut oil intake on attenuation of airway/nasal inflammation has not been widely studied. One study by Kamalaldin et al (2017) determined that the intrusion of inflammatory cells as well as the number of goblet and proliferative cells in the airway lumenwas significantly lower in VCO-treated allergic asthma models [115]. The authors also inferred that VCO performed better as a rescue agent rather than a preventive one in the case of asthma.…”
Section: Natural and Alternative Approachesmentioning
confidence: 99%