This paper takes the software industry base of national torch plan as the research object, describes its construction process and distribution characteristics for more than 20 years, and uses the cross-sectional data of 2007, 2012 and 2017, Empirically test the impact of software industry base on the service level of manufacturing industry in the region, and further analyze the regulatory effect of regional intellectual property protection intensity. It is found that the overall scale of the national software industry base has expanded steadily in recent 20 years, but the spatial distribution is extremely unbalanced. The software industry base in the eastern region is significantly stronger than that in the central and western regions in terms of base number and base income. The construction and development of software industry base can significantly improve the service level of manufacturing industry in the region. After the robustness test, the conclusion is still valid. The results of regional heterogeneity test show that with the deepening of industrialization, the construction of software industry base plays a more obvious role in improving the service-oriented manufacturing industry in the eastern region. The results of industry heterogeneity test show that the construction of software industry base can more effectively improve the service-oriented level of technology intensive manufacturing industry. The results of regulation effect test show that the strength of local intellectual property protection and strengthening the construction of software industry base have a positive regulation effect on the service level of manufacturing industry.