Does Intradialytic Exercise Improve Removal of Solutes by Hemodialysis? A Systematic Review and Meta-analysis

Intradialytic exercise in end-stage renal disease: An umbrella review of systematic reviews and/or meta-analytical studies

“…Discrepancies were resolved by discussion and consensus. The overall results showed that most reviews had critically low ( n = 5; 46%) 12,32–35 and low quality ( n = 4; 26%). 36–39 Several issues were found in the results of the meta-analyses since most of them did not assess or discuss heterogeneity ( n = 6, 60%), the implications of bias ( n = 9, 90%), or small-study effects ( n = 7, 70%).…”

“…Ten (91%) reviews reported the effects of aerobic exercise. 12,15,32–37,39,40 The duration of the programs ranged from three to 48 weeks; most sessions lasted more than 30 minutes (range: 5–90 minutes) and were performed two/three times a week. The exercise intensity was mainly assessed by the Rating of Perceived Exertion which ranged from 8 to 17 on a 6-20 Borg scale ( n = 7), or from two to six on a 1–10 modified Borg scale ( n = 5), followed by the percentage of perceived maximum effort ( n = 5; range: 40%–65%) and the percentage of oxygen consumption capacity (VO2peak; n = 4; range: 30%–75%).…”

“…Seven (64%) reviews reported the effects of resistance training. 15,32–34,36,39,40 The duration of the intervention programs ranged from eight to 36 weeks, with each session held two/three times a week. The training volume was reported by five reviews; it included 1–4 sets of 8–20 repetitions and 3–10 exercises with a 1-minute interval between sets.…”

“…Six reviews (55%) reported the effects of combining aerobic with resistance training during the dialysis session. 15,33,34,37,39,40 These programs lasted six to 48 weeks. The duration of each session ranged from 20 to 90 minutes and was performed two/three times a week.…”

“…Five reviews (46%) reported the effects of neuromuscular electrical stimulation. 15,33,36,38,40 These programs ranged from five to 20 weeks, each session lasted 20 to 60 minutes and was performed two/three times a week. The stimulation frequency varied from 5 to 80 Hz, while the pulse duration varied from 200 to 400 µs ( n = 3).…”