Does intranasal instillation TiO₂ cause pulmonary tumorigenesis in male mice?

Titanium dioxide particles from the diet: involvement in the genesis of inflammatory bowel diseases and colorectal cancer

“…This shows that the colitis caused by DSS facilitates absorption of TiO 2 nanoparticles, which was expected as colitis perturbs intestinal permeability. Finally, a series of articles from the Fashui Hong team reports impact of TiO 2 nanoparticles on diverse organs after oral administration, but these articles are not considered in this review because of flaws in the presentation and statistical analysis of the data, as has already been pointed out on a series of articles from the same team related to the pulmonary impact of similar TiO 2 nanoparticles [67]. In these articles the reported standard errors are exactly 5% of the reported mean, rather than the actual standard errors.…”