Does neuropsychological test performance predict resumption of drinking in posttreatment alcoholics?

Parsons, Oscar A.; Schaeffer, Kim W.; Glenn, Susan Wagner

doi:10.1016/0306-4603(90)90073-7

Cited by 77 publications

(55 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Similarly, in alcohol use disorders, there are relationships between treatment efficacy-outcome and neurocognitive functioning. Essentially, patients who exhibit more severe cognitive deficits have higher rates of relapse (Parsons et al, 1990).…”

Section: Discussionmentioning

confidence: 99%

Neurocognitive functioning in dually diagnosed middle aged and elderly patients with alcoholism and schizophrenia

Mohamed

Bondi

Kasckow

et al. 2006

Int J Geriat Psychiatry

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Neurocognitive functioning in dually diagnosed middle aged and elderly patients with alcoholism and schizophrenia

Mohamed

Bondi

Kasckow

et al. 2006

Int J Geriat Psychiatry

View full text Add to dashboard Cite

show abstract

“…The initial period of mild confusional state (with impairments in attention, memory and comprehension) has been termed the 'cognitive haze' [44] . Neuropsychological deficits have a negative impact on treatment compliance and outcome, both directly, and indirectly through the mediation of other factors [1,45] . Impairment of executive functions in alcohol-dependent patients has been associated with relapse, higher rates of attrition from treatment and rehabilitation [46] , and greater social functioning difficulties such as marital disruption [47] and employment failure [18] , all of which can contribute toward poor treatment outcomes.…”

Section: Discussionmentioning

confidence: 99%

Changes in Neuropsychological Functioning during Alcohol Detoxification

et al. 2008

View full text Add to dashboard Cite

This study investigates changes in neuropsychological functioning during early abstinence from alcohol. 30 alcohol-dependent inpatients were tested at intake (day 4 of admission) and post detoxification (day 26), using a test-retest design. The neuropsychological battery included measures of pre-morbid IQ, full-scale IQ, verbal and non-verbal measures of memory and executive function. IQ was within the normal range at intake and comparable with age-adjusted normative values and there were some impairments in memory and executive function. There were significant increases in performance scores post detoxification in working memory, verbal fluency and verbal inhibition but not in non-verbal executive function tasks (mental flexibility and planning ability). Despite increased scores on tests of verbal and memory skills after 3 weeks of abstinence, complex executive abilities showed little change. These may have a negative impact on engagement and response to treatment and compromise clinical outcomes, heightening the risk of relapse.

show abstract

“…One study (Bates et al, 2005) found a clinically significant, moderate effect size for change in memory in a large sample of alcoholics retested 6 weeks after entering treatment, whereas another (Mann et al, 1999) found no evidence for treatment-related improvements in memory tests after a comparable interval in a sample of 49 alcoholic men even though improvement occurred in other functional domains. Cross-sectional studies have shown that alcoholics sober for several months (Sullivan et al, 2000d;Sullivan et al, 2002;Meyerhoff, 2005;Rosenbloom et al, 2005), one year (Hochla et al, 1982;Parsons et al, 1990;Munro et al, 2000;Rosenbloom et al, 2004), or as long as seven years (Brandt et al, 1983) may still show memory deficits relative to non-alcoholic controls. However, other crosssectional studies have shown that performance on memory tests is related to length of abstinence (Joyce and Robbins, 1993;Oscar-Berman et al, 2004), and that alcoholics sober for more than 4 years are undistinguishable from controls on memory testing (Grant et al, 1984;Reed et al, 1992;Oscar-Berman et al, 2004;Fein et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Improvement in memory and static balance with abstinence in alcoholic men and women: Selective relations with change in brain structure

Rosenbloom

Rohlfing

O'Reilly

et al. 2007

Psychiatry Research: Neuroimaging

View full text Add to dashboard Cite

We investigated whether changes in memory or static balance in chronic alcoholics, occurring with abstinence or relapse, are associated with changes in lateral and fourth ventricular volume. Alcoholics meeting DSM-IV criteria for Alcohol Dependence (n = 15) and non-alcoholic controls (n = 26) were examined twice at a mean interval of two years with standard Wechsler Abbreviated Scale of Intelligence (WASI), Wechsler Memory Scale-Revised (WMS-R) tests, an ataxia battery, and structural MRI. At study entry, alcoholics had been abstinent on average for over 4 months and achieved lower scores than controls on WASI General IQ Index, WMS-R General Memory Index, and the ataxia battery. The ten alcoholics who maintained sobriety at retest did not differ at study entry in socio-demographic measures, alcohol use, or WASI and WMS-R summary scores from the five relapsers. At follow-up, abstainers improved more than controls on the WMS-R General Memory Index. Ataxia tended to improve in abstainers relative to controls. Associations were observed between memory and lateral ventricular volume change and between ataxia and fourth ventricular volume change in alcoholics but not in the controls. Both memory and ataxia can improve with sustained sobriety, and brain-behavior associations suggest selective brain structural substrates for the changes observed.

show abstract

Does neuropsychological test performance predict resumption of drinking in posttreatment alcoholics?

Cited by 77 publications

References 24 publications

Neurocognitive functioning in dually diagnosed middle aged and elderly patients with alcoholism and schizophrenia

Neurocognitive functioning in dually diagnosed middle aged and elderly patients with alcoholism and schizophrenia

Changes in Neuropsychological Functioning during Alcohol Detoxification

Improvement in memory and static balance with abstinence in alcoholic men and women: Selective relations with change in brain structure

Contact Info

Product

Resources

About