Does Obesity Affect the Severity of Exercise-Induced Muscle Injury?

Abstract

This is a PDF file of an article accepted, but it is not yet the definitive version of record.

Letter: Does Obesity Affect the Severity of Exercise-Induced Muscle Injury? (J Obes Metab Syndr 2021;30:132-40)

“…In fact, obese subjects have higher level of leptin, a pro-inflammatory adipokine, and lower level of adiponectin, an anti-inflammatory adipokine. 5 , 6 Kim and Yoon 1 reported that excess body fat is associated with increased levels of inflammatory markers such as interleukin-7 and C-reactive protein in postmenopausal women and in elderly obese women, supporting the relationship between obesity and inflammation. The researchers also underline that obesity-induced inflammatory responses are highly likely to contribute to the increase in post-exercise delayed onset muscle soreness (DOMS) severity.…”

“…1 Although the causes of DOMS are unclear, a major hypothesis suggests inflammatory responses as one cause. 1 Obesity is an important cardiovascular risk factor in women, especially visceral obesity that develops during menopause and is associated with high levels of inflammation. 2,7 Furthermore, obesity is associated with other co-morbidities that are no less dangerous than obesity itself, such as essential hypertension, atherosclerosis, coronary artery diseases, type 2 diabetes mellitus, and cerebrovascular stroke.…”

“…We have read with great interest the article “Does obesity affect the severity of exercise-induced muscle injury?” by Kim and Yoon 1 and found it of interest in prevention of muscle injury related to obesity. In this literature review, the authors investigated the effects of obesity on exercise-induced muscle injury and reexamined the potential mechanisms of exercise-induced muscle injury related to obesity.…”

“…The researchers also underline that obesity-induced inflammatory responses are highly likely to contribute to the increase in post-exercise delayed onset muscle soreness (DOMS) severity. 1 Although the causes of DOMS are unclear, a major hypothesis suggests inflammatory responses as one cause. 1 Obesity is an important cardiovascular risk factor in women, especially visceral obesity that develops during menopause and is associated with high levels of inflammation.…”

“… 1 Although the causes of DOMS are unclear, a major hypothesis suggests inflammatory responses as one cause. 1 Obesity is an important cardiovascular risk factor in women, especially visceral obesity that develops during menopause and is associated with high levels of inflammation. 2 , 7…”