Does physical exercise influence in the development of neuroeschistosomiasis?

Carvalho, Tiago Pinheiro Vaz de; Peixoto, Christina Alves; Paiva, Igor Henrique Rodrigues de; Loyo, Rodrigo Moraes; Nascimento, Wheverton Ricardo Correia do; Vasconcelos, Luydson Richardson Silva; Gomes, Elainne Christine de Souza; Barbosa, Constança Simões

doi:10.1016/j.brainresbull.2019.07.029

Cited by 1 publication

(1 citation statement)

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“…Patients with spinal cord schistosomiasis have increased levels of IL-1beta, IL-4, IL-6 and IL-10 and low concentrations of TNF-α and IFN-γ in both CSF and serum ( 238 ). In S. mansoni infected mice astrogliosis and microgliosis ( 228 ) were observed, as well as elevated IL-10 levels and decreased TNF-α expression ( 239 ). Thus, neuroschistosomiasis elicit a Th2 immune response in both humans and animals.…”

Section: Other Parasitesmentioning

confidence: 99%

Neuroimmunology of Common Parasitic Infections in Africa

et al. 2022

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Parasitic infections of the central nervous system are an important cause of morbidity and mortality in Africa. The neurological, cognitive, and psychiatric sequelae of these infections result from a complex interplay between the parasites and the host inflammatory response. Here we review some of the diseases caused by selected parasitic organisms known to infect the nervous system including Plasmodium falciparum, Toxoplasma gondii, Trypanosoma brucei spp., and Taenia solium species. For each parasite, we describe the geographical distribution, prevalence, life cycle, and typical clinical symptoms of infection and pathogenesis. We pay particular attention to how the parasites infect the brain and the interaction between each organism and the host immune system. We describe how an understanding of these processes may guide optimal diagnostic and therapeutic strategies to treat these disorders. Finally, we highlight current gaps in our understanding of disease pathophysiology and call for increased interrogation of these often-neglected disorders of the nervous system.

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Section: Other Parasitesmentioning

confidence: 99%