Does probiotics reduce crying time in infantile colic in exclusively breastfed babies? A comprehensive meta-analysis

Abstract

Background : Infantile colic is one of the common pediatric problems that Pediatricians encounter in practice. This condition is associated with excessive crying in healthy thriving infants over a regular period during the day and is sustained for the first few months of life. It has been historically described as irritable or compulsive crying or paroxysmal fussing with multifactorial etiology. Although it affects 5-19% of young infants, it remains a frustrating problem for parents and caregivers, because it is difficult to treat and may result in significant psychosocial consequences. Different treatment options are available with no definitive and conclusive benefit. In this metaanalysis, we pooled relevant data regarding the use of probiotics in infantile colic and tried to find out any beneficial effect thereof.