Current societal structures constantly oppress Black people and women. Black women are faced with a double dose of oppression; hence the term “misogynoir”. At work, they are often working twice as hard to prove to prove themselves. At home they are expected to be the perfect caregiver. It goes without saying that all this leaves little time for self-care. Their needs often go ignored by themselves and those around them. Where do THEY fit in this constant maelstrom of real and /or perceived responsibilities? How do they renew their sense of mental, physical and spiritual wellness? This chapter seeks to investigate the unique challenges Black women face in achieving a healthy work-life balance and discuss strategies that are being employed by women of color in various professional spheres. Self-care looks different to everyone. What works for one person may not necessarily work for another. This chapter will discuss different strategies and hopefully readers will find those that resonate with them and embark on the journey to thriving at work while practicing radical self-care.