2016
DOI: 10.1016/j.fertnstert.2016.07.843
|View full text |Cite
|
Sign up to set email alerts
|

Does the degree of sperm DNA fragmentation affect embryo aneuploidy rate

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3

Citation Types

0
3
0

Year Published

2022
2022
2022
2022

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(3 citation statements)
references
References 0 publications
0
3
0
Order By: Relevance
“…Decreased implantation rate reported in couples with malefactors (SMF and MMF) compare to N, as suggested by other researchers as well (Coates et al, 2017; Lei et al, 2021; Mazzilli et al, 2017). Similarly, several studies reported a higher frequency of aneuploidy in the case of a severe male factor compared with the normal male population (Gat et al, 2016, 2017; Magli et al, 2009; Pagidas et al, 2008). Interestingly, in binary logistic regression analysis, we found probability to obtaining ≥50% euploid rate in embryos of infertile couple is depended on sperm quality and determinant of the genetic quality (aneuploidy) of the embryo produced, as Oocyte has a potential to reverse sperm chromatin abnormalities with limited ability depend on the extent of damage, as evidenced in previously reported study by, (Magli et al, 2009) which concluded that SMF had decrease number of euploid embryos (55% aneuploidy rate with NZs, 62% with OZs and 69% with Obs‐AZs), biopsy on day three embryos with in situ hybridization of few chromosome was performed (Silber et al, 2003).…”
Section: Discussionmentioning
confidence: 81%
See 2 more Smart Citations
“…Decreased implantation rate reported in couples with malefactors (SMF and MMF) compare to N, as suggested by other researchers as well (Coates et al, 2017; Lei et al, 2021; Mazzilli et al, 2017). Similarly, several studies reported a higher frequency of aneuploidy in the case of a severe male factor compared with the normal male population (Gat et al, 2016, 2017; Magli et al, 2009; Pagidas et al, 2008). Interestingly, in binary logistic regression analysis, we found probability to obtaining ≥50% euploid rate in embryos of infertile couple is depended on sperm quality and determinant of the genetic quality (aneuploidy) of the embryo produced, as Oocyte has a potential to reverse sperm chromatin abnormalities with limited ability depend on the extent of damage, as evidenced in previously reported study by, (Magli et al, 2009) which concluded that SMF had decrease number of euploid embryos (55% aneuploidy rate with NZs, 62% with OZs and 69% with Obs‐AZs), biopsy on day three embryos with in situ hybridization of few chromosome was performed (Silber et al, 2003).…”
Section: Discussionmentioning
confidence: 81%
“…Higher level of DFI, CMI in male factor infertility, subsequently known to have negative impact on embryo kinetics, fertilization, implantation potential and live birth rate (Aoki et al, 2005;Mangoli et al, 2018;Oliva, 2006;Ozmen et al, 2007). Improve spermatogenesis before Increase in DFI and CM did not correlate with embryonic aneuploidy, complex abnormalities, trisomies and gonosomal aneuploidy could be to oocytes' potential to activate mechanism to arrest development of aneuploidy embryos (Gat et al, 2016(Gat et al, , 2017Magli, 2000;Magli et al, 2009;Mazzilli et al, 2017;Pagidas et al, 2008).…”
Section: Discussionmentioning
confidence: 93%
See 1 more Smart Citation