Does Tonsillectomy Increase Obesity Risk in Children with Down Syndrome?

Ruiz, Amanda G.; Gao, Dexiang; Ingram, David G.; Hickey, Francis; Haemer, Matthew; Friedman, Norman R.

doi:10.1016/j.jpeds.2019.04.019

Cited by 6 publications

(4 citation statements)

References 67 publications

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“…Problem obesity suffered by people with DS will Upgrade risk to problem other health . According to Esbensen (2010); Basil et al (2016);and Ruiz et al (2019), obesity own factor high risk for experience Obstructive Sleep Apnea (OSA) in adults with DS. In fact , some research ( Data in Table 2 explain how risk health other could suffered by children people with DS other than height risk obesity .…”

Section: Result(s)mentioning

confidence: 99%

Overcoming Health Risk of Down Syndrome Child with Obesity: Systematic Review

Swamilaksita

2022

Journal of ICSAR

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Down syndrome (DS) is a condition that occurs due to an abnormal number of chromosomes which is characterized by the presence of an additional chromosome. A child diagnosed with DS has three distinctive characters, namely having a low Intelligence Quotient (IQ), physical and mental limitations and having a weak immune system. Overweight and obesity are nutritional problems that often occur in people with DS, so it is necessary to study how the health risks that can be experienced by DS sufferers with obesity and how to overcome or minimize these risks. This Systematic Review study was conducted using the PubMed/Medline, Science Direct, and Google Scholar search databases. The search was limited to articles in peer-reviewed journals and literature reviews, which were written in English and Indonesian between 2012 and 2022. The study results showed that more than 40 percent of obesity occurred in children with DS. Obesity in people with DS can increase the risk of other health problems such as Obstructive Sleep Apnea (OSA) in adults with DS. In addition, dyslipidemia, hyperinsulinemia, NAFLD, Alzheimer's and tumors, and coronary heart disease are frequently reported in obese DS. Therefore, it is necessary to prevent nutritional problems by parents which includes parenting, feeding practices, and eating patterns. In addition, physical activity is needed for children with DS, especially for those who suffer from obesity. Fulfillment of nutrition and a healthy lifestyle throughout pregnancy is also needed to ensure the health of the child born and reduce the risk of having a baby with DS.

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Section: Result(s)mentioning

confidence: 99%

Overcoming Health Risk of Down Syndrome Child with Obesity: Systematic Review

Swamilaksita

2022

Journal of ICSAR

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“…A review of the literature conducted by Bertapelli et al demonstrated that the prevalence of being overweight and obese in children and youth with DS aged 0-19 years ranged from 23% to 70% [7]. The causes of overweight and obesity in children with DS include metabolic disorders, compulsive eating caused by difficulties in chewing food, muscle hypotonia leading to decreased satiety after meals and abnormal blood leptin levels, as well as comorbidities such as hypothyroidism [7,12,[14][15][16]. However, the studies do not provide clear results with respect to the genetic causes of obesity in children with intellectual disabilities.…”

Section: Introductionmentioning

confidence: 99%

Dietary habits, physical activity and nutritional status in children with Down’s syndrome

Wrzochal,

Sobaś,

Suliga

2023

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Introduction: To date, the risk factors for overweight and obesity in children with Down's syndrome (DS) have not been comprehensively described, as studies on the subject are rare and usually conducted among small groups.Aim of the research: To assess the dietary habits and physical activity, and their associations with nutritional status, in children with DS compared to a group of their typically developing peers. Material and methods: A sample of 102 children with DS and 107 children without SD aged 5-14 years. Eating habits were assessed using the patient's diary method over three days. Physical activity was measured using pedometers. Nutritional status was assessed based on body mass, height and fat percentage. Results: Children with DS had an excessive body mass index (p < 0.0001) and fat percentage (p < 0.0001) more often than the controls. They showed lower physical activity (p < 0.0001) and a higher risk of an insufficient intake of dietary fibre (p = 0.0113). Other factors potentially affecting body mass and fat percentage in children with DS included age, female gender and fewer underage family members. Conclusions: Physical activity in children with DS is insufficient to prevent chronic diseases. It is necessary to develop intervention programmes aimed at increasing participation in various forms of physical activity and changing their dietary habits. StreszczenieWprowadzenie: Czynniki ryzyka wystąpienia nadwagi i otyłości u dzieci z zespołem Downa (ZD) nie zostały dotąd wyczerpująco opisane, a badania w tym zakresie były podejmowane sporadyczne i prowadzone zazwyczaj w grupach o małych liczebnościach. Cel pracy: Ocena żywienia, poziomu aktywności fizycznej oraz ich powiązań ze stanem odżywienia u dzieci z ZD w porównaniu z grupą typowo rozwijających się rówieśników. Materiał i metody: Analizie poddano dane 102 dzieci z ZD oraz 107 dzieci bez ZD w wieku 5-14 lat. Sposób żywienia oceniono metodą bieżącego notowania przez 3 dni. Aktywność fizyczną zbadano za pomocą krokomierzy. Stan odżywienia badano na podstawie pomiarów masy i wysokości ciała oraz procentowej zawartości tkanki tłuszczowej. Wyniki: U dzieci z ZD częściej występowały nadmiary względnej masy ciała (BMI) (p < 0,0001), tkanki tłuszczowej (p < 0,0001), stwierdzono także niższy poziom aktywności fizycznej (p < 0,0001) i wyższe ryzyko niedostatecznego spożycia błonnika pokarmowego (p = 0,0113) w porównaniu z grupą kontrolną. Na wystąpienie większej masy ciała i większej ilości tkanki tłuszczowej u dzieci z ZD mogły mieć wpływ także takie czynniki, jak wiek, płeć żeńska i mniejsza liczba osób niepełnoletnich w gospodarstwie domowym. Wnioski: Aktywność fizyczna dzieci z ZD jest niewystarczająca, aby skutecznie zapobiegać rozwojowi chorób przewlekłych. Konieczne jest opracowanie programów interwencyjnych umożliwiających zwiększenie udziału tych dzieci w różnych formach aktywności fizycznej oraz zmiana nawyków żywieniowych.

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“…Smith et al also identified younger age as a predictor for increasing BMI z ‐score after AT, irrespective of whether the child had recurrent tonsillitis or OSA 8 . Furthermore, a 2017 publication by Ruiz et al, which analyzed a cohort of children with Down syndrome and OSA, demonstrated no change in the growth velocity after AT, regardless of OSA resolution 11 . Since obesity increases the risk of persistent OSA, some otolaryngologists may defer surgery due to the higher risk of weight gain and persistent OSA after AT and families may opt for nonsurgical treatment rather than exposing their child to both obesity and surgery.…”

Section: Introductionmentioning

confidence: 99%

Growth After Adenotonsillectomy for Obstructive Sleep Apnea: Revisited

et al. 2021

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Objectives/Hypothesis: To reanalyze the growth trajectory and assess longitudinal changes of children undergoing adenotonsillectomy (AT) versus watchful waiting (WW) enrolled in the Childhood Adenotonsillectomy Trial (CHAT) study and to determine if an AT increases the risk of obesity in children.Study Design: Reanalysis of prospective cohort investigation. Methods:The study analyzed publicly available data from CHAT, including 3 months visit data not previously included in a prior publication. Statistical comparisons and mixed-effects modeling were done using age-and sex-specific BMI expressed as a percentage of the 95th percentile (%BMIp95). P < .05 was considered significant.Results: Children in the AT group, especially if underweight at baseline, had an increased rate of weight gain, with 100% of underweight children in the AT group becoming normal weight compared to 20% for WW. However, the rate of weight gain, as measured by the %BMIp95 trajectory for both AT and WW groups, was not significantly different when baseline weight status and obstructive sleep apnea (OSA) resolution were accounted for. Comparisons of %BMIp95 between treatment groups at baseline, 3-and 7-month follow-up visits also failed to identify statistically significant differences (P > .05). Overall for the entire cohort, resolution of OSA was associated with a decreased weight trajectory (P < .001).Conclusions: AT compared to WW is not associated with an increased risk of excessive weight gain. Otolaryngologists should be aware of this updated analysis when discussing AT surgical outcomes with families.

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Does Tonsillectomy Increase Obesity Risk in Children with Down Syndrome?

Cited by 6 publications

References 67 publications

Overcoming Health Risk of Down Syndrome Child with Obesity: Systematic Review

Overcoming Health Risk of Down Syndrome Child with Obesity: Systematic Review

Dietary habits, physical activity and nutritional status in children with Down’s syndrome

Growth After Adenotonsillectomy for Obstructive Sleep Apnea: Revisited

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