2001
DOI: 10.1067/mai.2001.117797
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Dog exposure in infancy decreases the subsequent risk of frequent wheeze but not of atopy

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Cited by 254 publications
(170 citation statements)
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“…Although some studies have found positive associations (McConnell et al 2002;Zheng et al 2002), others have found pets to be protective (Hesselmar et al 1999;Remes et al 2001). In a review of 32 articles, presence of pets in the first 2 years of life was associated with a nonsignificant 11% increase in asthma risk (Apelberg et al 2001).…”
Section: Discussionmentioning
confidence: 99%
“…Although some studies have found positive associations (McConnell et al 2002;Zheng et al 2002), others have found pets to be protective (Hesselmar et al 1999;Remes et al 2001). In a review of 32 articles, presence of pets in the first 2 years of life was associated with a nonsignificant 11% increase in asthma risk (Apelberg et al 2001).…”
Section: Discussionmentioning
confidence: 99%
“…La relación entre exposición a animales domésticos y el desarrollo de enfermedades respiratorias alérgicas en la niñez es controvertida. Aunque algunos estudios han mostrado que la exposición a estos alérgenos se asocia con prevalencia de asma y exacerbaciones de la enfermedad 26,27 , otros estudios sugieren que la exposición temprana a estos animales puede reducir el riesgo de desarrollar síntomas alérgicos, asma y sibilancias 28,29,30,31,32 . En este sentido se ha propuesto la teoría de que altas exposiciones a productos microbianos, como endotoxinas bacterianas, a edades tempranas puede mediar inmunológica-mente este efecto protector, especialmente en áreas metropolitanas 33,34,35 .…”
Section: Discussionunclassified
“…Sticking with well-performed, longitudinal studies, two recent birth cohort studies in US metropolitan communities have found less subsequent asthma in children raised with pet dogs [11], and less subsequent allergen sensitization with increasing numbers of pet cats and/or dogs in early life [12]. In a third birth cohort study, dog ownership in particular was associated with less atopic dermatitis, less food allergy, and less allergen sensitization at 1 year of age [13].…”
mentioning
confidence: 89%