Domain wall mobility in Permalloy films has been calculated as a function of thickness at 10, 80, and 160 nm which reflects the structure change of Néel, symmetric Bloch and C-shaped (asymmetric Bloch) domain walls. The mobility has been derived from the dynamics of a single nonperiodic domain wall using direct integration of the Landau–Lifshitz–Gilbert equation in a Cartesian lattice. This investigation allows for a detailed examination of spin precession, wall motion and overall magnetization distortion as the wall is moved in the presence of fields ranging from 0.5 to 5 Oe applied in the easy axis direction. At 10-nm-thick films, the mobility of a Néel wall is 30 m/s Oe. Wall motion takes place without noticeable distortion in the magnetization distribution in the vicinity of the Néel wall. For 80 nm-thick films, the mobility of a symmetric Bloch wall is 5 m/s Oe, or 20% less than the theoretical prediction for the mobility of a 180° domain wall model. At dynamic equilibrium, the symmetric Bloch wall has been slightly distorted into a C-shaped wall. For 160 nm-thick films, the mobility of a C-shaped wall is 12 m/s Oe, or 29% less than the theoretical predicted value. Shearing-type magnetization distortion is observed in this composite structure of a Bloch component at the center and Néel caps of opposite chirality at the surfaces.