In this article, we focus on dominating set problems in graphs. We review the literature that analyzes domination from different aspects, including bounds for the domination number, the algorithmic complexity, and valid inequality chains associated with each domination variant. In particular, we discuss the relationship between domination, independence, and irredundance, and reveal the well‐known domination chain and its properties. As many domination‐related problems can be solved in polynomial time for certain types of graphs (e.g., trees), we summarize start‐of‐the‐art results of polynomial algorithms regarding the domination‐related parameters of graphs. We also describe applications such as wireless ad hoc networks, social networks, and broadcast domination in which domination or its variants can be suitably implemented, as well as associated approximation algorithms, in order to emphasize the importance of the domination in graphs from a practical perspective.