Don’t dust off the dust! – A facile synthesis of graphene quantum dots derived from indoor dust towards their cytotoxicity and antibacterial activity

Raju, Liju; Jacob, Megha Sara; Rajkumar, Eswaran

doi:10.1039/d2nj02876j

Cited by 2 publications

(1 citation statement)

References 63 publications

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“…GQDs exhibit very good photodynamic antibacterial characteristics [26,237]. However, researchers often use them to create nanocomposites with other nanoparticles, and improve their characteristics [238].…”

Section: Antibacterial Pdt With Gqds and Cqds As Agentmentioning

confidence: 99%

Lights and Dots toward Therapy—Carbon-Based Quantum Dots as New Agents for Photodynamic Therapy

et al. 2023

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The large number of deaths induced by carcinoma and infections indicates that the need for new, better, targeted therapy is higher than ever. Apart from classical treatments and medication, photodynamic therapy (PDT) is one of the possible approaches to cure these clinical conditions. This strategy offers several advantages, such as lower toxicity, selective treatment, faster recovery time, avoidance of systemic toxic effects, and others. Unfortunately, there is a small number of agents that are approved for usage in clinical PDT. Novel, efficient, biocompatible PDT agents are, thus, highly desired. One of the most promising candidates is represented by the broad family of carbon-based quantum dots, such as graphene quantum dots (GQDs), carbon quantum dots (CQDs), carbon nanodots (CNDs), and carbonized polymer dots (CPDs). In this review paper, these new smart nanomaterials are discussed as potential PDT agents, detailing their toxicity in the dark, and when they are exposed to light, as well as their effects on carcinoma and bacterial cells. The photoinduced effects of carbon-based quantum dots on bacteria and viruses are particularly interesting, since dots usually generate several highly toxic reactive oxygen species under blue light. These species are acting as bombs on pathogen cells, causing various devastating and toxic effects on those targets.

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Section: Antibacterial Pdt With Gqds and Cqds As Agentmentioning

confidence: 99%

Lights and Dots toward Therapy—Carbon-Based Quantum Dots as New Agents for Photodynamic Therapy

et al. 2023

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Development of graphene and graphene quantum dots toward biomedical engineering applications: A review

Handayani,

Hendrik,

Abbas

et al. 2023

Nanotechnology Reviews

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Research on the application of graphene (G) and graphene quantum dots (GQDs) for biomedical engineering has attracted much attention over the last decade. Graphene and its derivatives have shown great biocompatibility, solubility, selectivity, large surface area, high purity, biofunctionalization, high drug loading capacity, and cell membrane penetration capability potential to be applied in biomedical engineering areas. The unique physical and chemical properties of GQDs, including small size, chemical inertness, high photoluminescence stability, low cytotoxicity, and good biocompatibility, made them a promising candidate for biomedical engineering applications. The recent progress related to the development of G and GQDs toward biomedical engineering applications is presented in this work. This study reviews and discusses the development of G and GQDs, both top-down and bottom-up synthesis methods, for biomedical engineering applications, such as biosensing, tissue engineering, drug delivery, bioimaging, antibacterial, and antiviral.

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Don’t dust off the dust! – A facile synthesis of graphene quantum dots derived from indoor dust towards their cytotoxicity and antibacterial activity

Abstract: We have attempted the synthesis of crystalline graphene quantum dots (GQDs) from indoor dust particles; a ubiquitous waste material with no practical applications. A simple and facile hydrothermal approach was...

Cited by 2 publications

References 63 publications

Lights and Dots toward Therapy—Carbon-Based Quantum Dots as New Agents for Photodynamic Therapy

Lights and Dots toward Therapy—Carbon-Based Quantum Dots as New Agents for Photodynamic Therapy

Development of graphene and graphene quantum dots toward biomedical engineering applications: A review

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