Donor-derived fatal hyperinfection strongyloidiasis in renal transplant recipient

Three Autochthonous Cases of Strongyloidiasis: An Endemic Tropical Disease Underdiagnosed in Portugal

“…Strongyloides stercoralis is a nematode with worldwide distribution, and a frequent cause of infection in tropical and subtropical regions. [1][2][3][4][5] Although sporadic imported and autochthonous cases have been described in Southern Europe, [3][4][5] there is no recent epidemiological data from Portugal.…”

“…Peripheral intermittent eosinophilia is common, but its absence does not exclude the diagnosis. 1 In immunocompromised individuals (particularly those with impaired cellular immunity), 3 hyperinfection syndrome may occur: an accelerated autoinfection cycle with disseminated strongyloidiasis, associated with a high morbimortality. Therefore, eradication is particularly important in immunosuppressed or immunosuppression candidates.…”

“…Therefore, eradication is particularly important in immunosuppressed or immunosuppression candidates. 1,3 In 2020, Pinto et al 1 presented one of the first autochthonous cases of strongyloidiasis in Portugal since 1985 5 : the case of a 69-year-old farmer with abdominal pain and eosinophilia.…”

Prevalence of strongyloidiasis among cardiothoracic organ transplant candidates in a non‐endemic region: A single‐center experience with universal screening

“…4 Chronic strongyloidiasis can lead to hyperinfection and dissemination in the setting of immunosuppression, including after solid organ transplantation (SOT). [5][6][7][8] Disseminated Strongyloides infection has high rates of morbidity and mortality and is frequently complicated by gram-negative sepsis and meningitis. 9 Screening and treatment for strongyloidiasis during the pretransplant evaluation of patients can reduce the risk of post-transplant disseminated infection.…”