Donor experience and outcome of pediatric living-related liver transplantation in Saudi Arabia

Al-Shurafa, Haider A.; Jawdat, Muaffak; Wali, Sami; Chehab, May; Shahid, M. K.; Djuberg, Hans; Bassas, Atef F.

doi:10.1007/s00534-002-0833-4

Cited by 5 publications

(7 citation statements)

References 11 publications

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“…To date, more than 200 LDLTs have been performed in Saudi Arabia, divided between three main LT centers. 6 – 9 Along with Egypt, Saudi Arabia was one of the leading countries in the field of LDLT in the Middle East. 10 – 12 The LT program at King Faisal Specialist Hospital and Research Center (KFSHRC) was first established in 1994.…”

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confidence: 99%

Experience with 122 consecutive liver transplant procedures at King Faisal Specialist Hospital and Research Center

Al-Sebayel

Khalaf

Al-Sofayan

et al. 2007

Annals of Saudi Medicine

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BACKGROUNDSaudi Arabia is a leading country in the Middle East in the field of deceased-donor liver transplantation (DDLT) and living-donor liver transplantation (LDLT). We present out experience with DDLT and LDLT at King Faisal Specialist Hospital and Research Center (KFSHRC) for the period from April 2001 to January 2007.PATIENTS AND METHODSWe performed 122 LT procedures (77 DDLTs and 45 LDLTs) in 118 patients (4 retransplants) during this period of time.RESULTSThe number of adult and pediatric procedures was 107 and 11, respectively. The overall male/female ratio was 66/52 and the median age of patients was 43 years (range, 2–63 years). In the DDLT group, the median operating time was 8 hours (range, 4–19), the median blood transfusion was 6 units (range, 0–40), and the median hospital stay was 13 days (range, 6–183). In the DDLT group, after a mean follow-up period of 760 days (range, 2–2085), the overall patient and graft survival rate was 86%. In the LDLT group, the median operating time was 11 hours (range, 7–17), the median blood transfusion was 4 units (range, 0–65), and the median hospital stay was 15 days (range, 7–127). In the LDLT group, and after a mean follow-up period of 685 days (range, 26–1540), the overall patient and graft survival rates were 90% and 80%, respectively with no significant difference in patient and graft survivals between groups. Biliary complications were significantly higher in LDLT compared to DDLT (P<0.05). Vascular complications were also significantly higher in LDLT compared DDLT (P<0.05).CONCLUSIONSBoth DDLT and LDLT are being successfully performed at KFSHRC with early experience indicating a higher rate of biliary and vascular complications in the LDLT group.

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confidence: 99%

Experience with 122 consecutive liver transplant procedures at King Faisal Specialist Hospital and Research Center

Al-Sebayel

Khalaf

Al-Sofayan

et al. 2007

Annals of Saudi Medicine

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“…7 This review presents a series of live donation of the larger right liver grafts from adult donors needed to meet the metabolic demands of adult recipients.…”

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confidence: 99%

Living Donor Liver Transplantation: Perioperative Experience From Saudi Arabia

Yassen

Kareem²

2006

International Anesthesiology Clinics

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“…Ein besonderes Operationsrisiko sollte für diese Patienten der ASA-Klassifikation Gruppe 1 bis maximal 2 nicht bestehen, sodass nur das eigentliche Operationsrisiko bestehen bleibt. Die Eigenschaften der Spender in der vorliegenden Arbeit ähneln den Charakterisierungen von Spenderpopulationen aus anderen internationalen Transplantationszentren [12,13], was den hohen Sicherheitsaspekt der verschiedenen Zentren widerspiegelt und die konkordante Einschätzung der relevanten Kriterien zur Spenderauswahl bestätigt. Die intraoperativen Verläufe zeigen, dass der komplexe Eingriff einer linkslateralen Leberresektion mit hoher Sicherheit durchgeführt werden kann.…”

Section: Methodik Der Spenderevaluationunclassified

Linkslaterale Leberlebendspende – Erfahrungen aus Essen

et al. 2013

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The international organ shortage for liver transplantation exists particularly in paediatric transplantation. Therefore left-lateral living related liver donation (LLRLD) plays a major role in this field. The aim of the present study was to analyse all procedures of LLRLD in terms of donor safety from December 2008 to October 2012 at the University Hospital of Essen, Germany. All procedures of LLRLD from December 2008 to October 2012 at the University Hospital of Essen were included in the present study. All operations were carried out via an open narrowed median longitudinal laparotomy. General donor data were analysed. Complications were recorded and classified in accordance to their relevance. 35 LLRLD were performed between December 2008 and October 2012 at the University Hospital of Essen, Germany. Mean age of the donors was 31.9 (23.4-61.7) years and 60 % were female. Past medical histories of the donors showed no relevant diagnoses. Mean length of the surgical procedure was 180 (± 89) minutes. Survival rate was 100 %. Minor complications were seen in 1 of 35 patients. Laboratory data showed a peak of the transaminases on the first postoperative day which resolved during the further course. Median postoperative hospital stay was 7 (5-11) days. LLRLD can be performed safely for the donors after adequate donor selection. The organ pool for paediatric recipients can be expanded by this procedure at suitable transplant centres.

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Donor experience and outcome of pediatric living-related liver transplantation in Saudi Arabia

Cited by 5 publications

References 11 publications

Experience with 122 consecutive liver transplant procedures at King Faisal Specialist Hospital and Research Center

Experience with 122 consecutive liver transplant procedures at King Faisal Specialist Hospital and Research Center

Living Donor Liver Transplantation: Perioperative Experience From Saudi Arabia

Linkslaterale Leberlebendspende – Erfahrungen aus Essen

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