Donor Eyes A Comparison of Characteristics and Outcomes for Eye Bank and Local Tissue

Ml, Chipman; Willett, P. J.; Pk, Basu; Wolf, Armin

doi:10.1097/00003226-198903000-00011

Cited by 6 publications

(4 citation statements)

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“…The differences in the risk of failure between donors dying of disease in injury may explain the slightly better survival rates associated with locally acquired eyes in the earlier study (Chipman 1989). It may also mean that Eye Banks which obtain a larger proportion of their tissue from accident victims and others dying of violence have an advantage over those relying more heavily on other sources of tissue.…”

Section: Discussionmentioning

confidence: 81%

“…Since October 1985, the Corneal Recipient Registry has been collecting information on tissue donors regardless of Eye Bank involvement. A comparison of Eye Bank and local tissue has revealed many differences: donor age, cause of death, time to enucleation, and methods of storage (Chipman et al 1989). Procedures using local tissue also had somewhat better graft survival.…”

mentioning

confidence: 99%

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The effects of donor age and cause of death on corneal graft survival

Chipman

Basu

Willett

et al. 1990

Acta Ophthalmologica

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The Ontario Corneal Recipient Registry followed 299 recipients of 326 corneal transplants performed between October 1985 and October 1987. This report describes the joint effects of donor age and cause of death on subsequent graft survival in these procedures up to two years after surgery. Cox regression analysis established that grafts from donors dying of injury experienced half the risk of graft failure of those from donors dying of heart disease or other natural causes (P less than 0.05). Although donor age differed substantially between these causes of death, controlling for donor age did not alter the association. There were no statistically or clinically significant differences in graft survival associated with either donor age or recipient age. These results suggest that the health of the donor and the circumstances surrounding death may influence the quality of corneal tissue, and deserve more attention and detailed study.

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Section: Discussionmentioning

confidence: 81%

mentioning

confidence: 99%

The effects of donor age and cause of death on corneal graft survival

Chipman

Basu

Willett

et al. 1990

Acta Ophthalmologica

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“…1989-1993: Donor tissue characteristics and transplant outcomes, 20,128 and risk for early transplant failure. 129 Data were collected from 9 centers in Ontario.…”

Section: Data Elementsmentioning

confidence: 99%

“…10,23,31,32 Surgical procedures were commonly divided by surgical types as penetrating keratoplasty (PK), endothelial keratoplasty (EK), or anterior lamellar keratoplasty (ALK) 15,33,34 or by the treatment purposes as optical, therapeutic, or tectonic transplant. 22,31,35 Several registries Canada (ON), 1985 128 Regional, multicentered 20 (n/a)…”

Section: Data Elementsmentioning

confidence: 99%

Keratoplasty Registries: Lessons Learned

Chu

Liu

et al. 2022

Cornea

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:Clinical registries have been developed for decades in the field of ophthalmology, and they are especially well-suited to the study of keratoplasty practices. A comprehensive donor/recipient registry system can provide insight into donor, recipient, and surgical factors associated with immediate and long-term outcomes and adverse reactions. Furthermore, linkage with demographic databases can elucidate relationships with social determinants of health and potentially shape public policy. The vast sample size and multicenter nature of registries enable researchers to conduct sophisticated multivariate or multilayered analyses. In this review, we aim to emphasize the importance of registry data for keratoplasty practice and 1) summarize the structure of current keratoplasty registries; 2) examine the features and scientific contributions of the registries from Australia, the United Kingdom, Singapore, the Netherlands, Sweden, Eye Bank Association of America, and European Cornea and Cell Transplant registries; 3) compare registry-based studies with large single-site clinical studies; 4) compare registry-based studies with randomized control studies; and 5) make recommendations for future development of keratoplasty registries. Keratoplasty registries have increased our knowledge of corneal transplant practices and their outcomes. Future keratoplasty registry-based studies may be further strengthened by record linkage, data sharing, and international collaboration.

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Primary Corneal Graft Failure

Rd²,

Sugar³

et al. 1995

Arch Ophthalmol

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Donor Eyes A Comparison of Characteristics and Outcomes for Eye Bank and Local Tissue

Cited by 6 publications

References 0 publications

The effects of donor age and cause of death on corneal graft survival

The effects of donor age and cause of death on corneal graft survival

Keratoplasty Registries: Lessons Learned

Primary Corneal Graft Failure

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