Donor Infection: An Opinion on Lung Donor Utilization

Bacterial meningitis as a cause of death in lung transplant donors: Early outcomes in recipients

“…Our study is limited by its retrospective observational design, which is limited by missing donor data. However, our results are consistent with findings of other observational studies . To date, there is no standard protocol to compare our strategies in lung transplantation with donors who died of bacterial meningitis.…”

“…Infections continue to remain the primary cause of mortality during the first year after lung transplantation and transmission of bacterial and/or fungal infections from donor to recipient have been documented following solid organ transplantation . Consequently, a potential donor with an active infection is often turned down for organ procurement.…”

Manuseio do potencial doador de múltiplos órgãos

“…Não há aumento na mortalidade ou na morbidade a curto (um ano) e médio (cinco anos) prazos associado com o transplante de fígado de doadores HCV+ quando comparado a doadores HCV-, seja em receptores HCV+, seja em HCV- 46 . A sobrevida dos enxertos renais em 10 anos também não é afetada pela sorologia de hepatite C do doador 47 . O receptor HCV+ é o receptor ideal de órgãos HCV+, mas as urgências na lista de espera precisam ser consideradas.…”

“…Citomegalovírus transmitido através de órgãos sólidos causa infecção e doença nos receptores, especialmente nos receptores CMV-. Profi laxia de rotina contra CMV reduz expressivamente a morbimortalidade associada à infecção por esse vírus 47 . Sepse e choque séptico não inviabilizam a doação de órgãos, desde que o doador esteja recebendo antibiótico.…”

Bacterial Infection during Adult Donor Care

“…They include, for example, aseptic techniques for insertion of vascular/ urinary catheters; scheduled changes for ventilator circuits, vascular catheters, and catheter dressings; providing "closed" systems for urinary drainage, endo tracheal suctioning, or evacuation of cerebrospinal fluid; head elevation to minimize aspiration risk; and administration of medications to reduce the number of abnormal pharyngeal bacteria. 3,14 Although the time between consent and organ removal during donor care may be short, these practices should be continued.…”