Donor selection in Japan: a trial of new criteria with predonation haemoglobin testing

Shimoyama, Rai; Nakase, Toshie; Kojima, Seiji; Tanaka, Satomi; Yamamori, Kunio; Kaneko, Chikara; Ishimaru, Kaori; Ikeda, Hiromi

doi:10.1046/j.0042-9007.2001.00145.x

Cited by 1 publication

(1 citation statement)

References 8 publications

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“…Prior to their first blood donation, premenopausal women in the UK may be functionally replete in iron but have minimal stores. The normal range of venous blood Hb in non-pregnant younger women in the UK and Japan is close to 130 AE 9 g L kg 21 (mean and SD - White et al, 1993;Shimoyama et al, 2002). These surveys apply to racial groups with low prevalence of haemoglobinopathies and thalassaemias and of comparable nutritional status, although the British Nutrition Foundation (1995) attributed variable Hb in different racial groups in British cities mainly to nutrition.…”

Section: Donation-induced Iron Depletion and Deficiencymentioning

confidence: 99%

Evidence‐based criteria for the care and selection of blood donors, with some comments on the relationship to blood supply, and emphasis on the management of donation‐induced iron depletion

Boulton¹

2008

Transfusion Medicine

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Blood Services, which, in the UK, spend over 0.5% of the NHS budget, are generally subject to quality, regulatory, economic and political authority. As only persons in good health should give blood, Services have refined donor selection criteria and aim to base them on evidence; but they also have to balance the number of donations collected with product demand. Applying selection criteria inevitably leads to deferrals, which donors experience very negatively. Compared with successful donors, even temporary deferrals reduce return rates significantly, especially of first attenders. In order to encourage donor return and sustain supplies, selection criteria should be optimal. However, a major tool for managing patients--evidence from randomized controlled trials (RCTs)--cannot apply to donor selection, so criteria have to be defined by alternatives, such as clinical studies, epidemiology and even what experts deem to be pathophysiologically feasible. The recommended volume of blood taken from each donor at each attendance (450 mL, which was based on old studies) was increased because of greater processing losses (buffy-coat derived platelets, leucofiltration etc.). Although faint rates and donation-induced iron depletion are reduced by lowering bleeding volume and bleeding less frequently, other optimizing strategies including iron supplementation have been trialled and could be enhanced by more RCTs. Better but more complex indicators of donor iron status than one-off Hb thresholds are possible. Regulators and decision-makers must encourage more studies. This review does not consider aphaeresis donors of blood components other than red cells in detail, or the prevention of transfusion-transmitted infections.

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Section: Donation-induced Iron Depletion and Deficiencymentioning

confidence: 99%

Evidence‐based criteria for the care and selection of blood donors, with some comments on the relationship to blood supply, and emphasis on the management of donation‐induced iron depletion

Boulton¹

2008

Transfusion Medicine

View full text Add to dashboard Cite

show abstract

Donor selection in Japan: a trial of new criteria with predonation haemoglobin testing

Abstract: Predonation measurement of haemoglobin concentration, combined with the referral of those with abnormal values, provided a health benefit to that population.

Cited by 1 publication

References 8 publications

Evidence‐based criteria for the care and selection of blood donors, with some comments on the relationship to blood supply, and emphasis on the management of donation‐induced iron depletion

Evidence‐based criteria for the care and selection of blood donors, with some comments on the relationship to blood supply, and emphasis on the management of donation‐induced iron depletion

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