1983
DOI: 10.1111/j.1365-2125.1983.tb02154.x
|View full text |Cite
|
Sign up to set email alerts
|

Dopaminergic control of gastric acid and gastrin secretion in man: lack of effects after acute oral administration of ibopamine, an analogue of dopamine.

Abstract: The effect of oral administration of the dopaminergic drug, ibopamine, at the dose of 200 mg and 400 mg, on basal and submaximal pentagastrin (0.25 ,ug kg-l h-) stimulated gastric acid secretion as well as basal serum gastrin concentration has been evaluated in 24 healthy individuals. In comparison with placebo no significant changes were observed in all the variables studied. The lack of effects on gastric acid secretion might be due to a selective stimulation of dopaminergic receptors not active in the regul… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

1985
1985
1991
1991

Publication Types

Select...
3
1

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(1 citation statement)
references
References 13 publications
0
1
0
Order By: Relevance
“…This is probably an underestimated value; owing to analytical difficulties, only free and not conjugated DOPAC and HVA were taken into account. The urinary conjugates of epinine were identified as the predominant epinine 4-0-glucuronide ( I ) (about 70% of the recovered dose), with a small amount (2%) of epinine 3-0sulfate (6). Epinine 3-0-methyl ether was also present in a significant amount (10%) in the glucuronide fraction; DOPAC and HVA accounted for the difference.…”
Section: Metabolism and Pharmacokineticsmentioning
confidence: 99%
“…This is probably an underestimated value; owing to analytical difficulties, only free and not conjugated DOPAC and HVA were taken into account. The urinary conjugates of epinine were identified as the predominant epinine 4-0-glucuronide ( I ) (about 70% of the recovered dose), with a small amount (2%) of epinine 3-0sulfate (6). Epinine 3-0-methyl ether was also present in a significant amount (10%) in the glucuronide fraction; DOPAC and HVA accounted for the difference.…”
Section: Metabolism and Pharmacokineticsmentioning
confidence: 99%