2024
DOI: 10.1007/s00259-024-06961-x
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Dopaminergic PET to SPECT domain adaptation: a cycle GAN translation approach

Leonor Lopes,
Fangyang Jiao,
Song Xue
et al.

Abstract: Purpose Dopamine transporter imaging is routinely used in Parkinson’s disease (PD) and atypical parkinsonian syndromes (APS) diagnosis. While [11C]CFT PET is prevalent in Asia with a large APS database, Europe relies on [123I]FP-CIT SPECT with limited APS data. Our aim was to develop a deep learning-based method to convert [11C]CFT PET images to [123I]FP-CIT SPECT images, facilitating multicenter studies and overcoming data scarcity to promote Artificial Intelligence (AI) advancements. … Show more

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