Doppler Echocardiographic Assessment of Valvular Heart Disease in Patients Requiring Hemodialysis for End-Stage Renal Disease

Stinebaugh, J.; Lavie, Carl J.; Milani, R.V.; Cassidy, Mark M.; Figueroa, Julio E.

doi:10.1097/00007611-199501000-00009

Cited by 22 publications

(10 citation statements)

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“…The prevalence of aortic valve calcification is higher in patients with CKD than in the general population and dialysis has been proposed to be an independent risk factor for aortic valve calcification [1,2,3,4,5,6,7,8,9]. Different studies on SAVR in dialysis patients have been performed [16,17,18], showing an increased surgical risk in these patients.…”

Section: Discussionmentioning

confidence: 99%

“…One potential reason might be the faster progression rate of cardiac valvular calcification in patients with ESRD compared to the normal population [1,2,3,4,5,6,7,8,9]. The higher EuroSCORE reflects the poor preinterventional clinical status of these patients, making them not suitable for open surgery.…”

Section: Discussionmentioning

confidence: 99%

“…In patients on chronic hemodialysis, aortic valve calcification is present in 25–55% and it occurs 10–20 years earlier than in the general population [1,2,3,4,5,6,7,8,9]. Pathophysiology and the rate of progression of cardiac valvular calcification in patients with ESRD appear to be different from those in the general population, with secondary hyperparathyroidism being one of the most important predisposing factors.…”

Section: Background/aimsmentioning

confidence: 99%

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Transcatheter Aortic Valve Implantation in Dialysis Patients

Rau¹,

Lange

Kupatt

et al. 2012

Nephron Clin Pract

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Background/Aims: Transcatheter aortic valve implantation (TAVI) has emerged as a new therapeutic option for high-risk patients. However, dialysis patients were excluded from all previous studies. The aim of this study is to compare the outcomes of TAVI for dialysis patients with those for patients with chronic kidney disease (CKD) stages 3 and 4 and to compare TAVI with open surgery in dialysis patients. Methods: Part I: comparison of 10 patients on chronic hemodialysis with 116 patients with non-dialysis-dependent CKD undergoing TAVI. Part II: comparison of transcatheter (n = 15) with open surgical (n = 24) aortic valve replacement in dialysis patients. Results: Part I: dialysis patients were significantly younger (72.3 vs. 82.0 years; p < 0.01). Hospital stay was significantly longer in dialysis patients (21.8 vs. 12.1 days; p = 0.01). Overall 30-day mortality was 3.17%, with no deaths among dialysis patients. Six-month survival rates were similar (log-rank p = 0.935). Part II: patient age was comparable (66.5 vs. 69.5 years; p = 0.42). Patients in the surgical group tended to stay longer in hospital than TAVI patients (29.5 vs. 22.5 days; p = 0.35). Conclusion: TAVI is a safe procedure in patients on chronic hemodialysis. Until new data become available, we find no compelling reason to refuse these patients TAVI.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Background/aimsmentioning

confidence: 99%

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Transcatheter Aortic Valve Implantation in Dialysis Patients

Rau¹,

Lange

Kupatt

et al. 2012

Nephron Clin Pract

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“…In accordance with previous studies, preoperative organ dysfunction correlated with patient characteristics and morphology and function of the left side of the heart. 18,19 In addition, preoperative renal and liver dysfunction were associated with dilatation of the right heart and worse RV function, but not with TR. If one believes that functional TR is caused by pulmonary congestion, elevated pulmonary artery pressure, and RV dilatation and dysfunction, it makes sense that right heart morphology and function may be of more prognostic importance than TR and suggests that we pay more attention to right heart morphology and RV function when evaluating patients with degenerative mitral valve disease who have impaired kidney and liver function.…”

Section: Risk Factors For Preoperative Organ Dysfunctionmentioning

confidence: 97%

Effects of right ventricular morphology and function on outcomes of patients with degenerative mitral valve disease

Desai

Abello

et al. 2014

The Journal of Thoracic and Cardiovascular Surgery

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Together with patient comorbidities and operative factors, right ventricular morphology and function are associated more strongly with preoperative organ dysfunction and prognosis than is functional tricuspid regurgitation severity in patients undergoing surgery for degenerative mitral valve disease. Our previous study showed that tricuspid valve repair remains the most effective treatment to improve right ventricular function.

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“…Aortic sclerosis has a higher prevalence in certain patient subgroups. For example, it is found in 55-69% of patients with end stage renal disease on hemodialysis [5,6].…”

Section: Prevalencementioning

confidence: 99%