Conclusion: Coronary-pulmonary artery fistula in adults was found more often than in previous studies. CAF commonly originates from LCA or both LCA and RCA in adults. DSCT is a robust tool for investigating the origin, course and drainage site of CAF and coexistent abnormalities. Advances in knowledge: A large adult patient cohort who underwent DSCT angiography was reviewed to assess CAFs. Coronary-pulmonary artery fistula in adults was found more often than in previous studies. CAF was observed to originate from the LCA or both coronary arteries in adults. DSCT could clearly depict the fistula origin, course, drainage site and coexisting abnormalities. Conventional angiography results, treatments and followup DSCT images were analysed.Coronary artery fistulas (CAFs) are anomalous connections of the coronary arteries. The phenomenon was first described in 1865 by Krause. 1 CAF is considered as a major coronary anomaly by Ogden's classification.2 Most CAFs are congenital. CAFs have an estimated prevalence of 0.002% in the general population; however, they are present in 0.05-0.25% of patients who undergo coronary angiography.3-5 The traditional diagnosis tool for CAFs is conventional angiography. With the advent of 64-slice multidetector CT in chest and cardiac imaging, the number of incidentally found CAFs has been increasing. The advanced electrocardiogram (ECG)-gated technique of dual-source CT (DSCT) could provide high diagnostic accuracy for the assessment of coronary artery disease.According to prior studies, CAF arises from the right coronary artery (RCA) in approximately 50% of patients. [6][7][8] In particular, 70% of the CAFs in children (mean age, 2.9 years) originated from the RCA. 9 In this study, we focused on adult patients. A large cohort of adult patients who underwent DSCT angiography was reviewed to assess CAFs. The CAFs and coexisting abnormalities were analysed.
METHODS AND MATERIALS PatientsA total of 17,548 patients who were suspected of having coronary artery disease underwent contrast-enhanced CT angiography (CCTA) from January 2008 to October 2013 in Peking Union Medical College Hospital, Beijing, China. The CCTA reports and images were retrospectively reviewed. Four experienced radiologists reviewed the axial, maximum intensity projection and volume rendering technique images of all 17,548 patients through the picture archiving and communication system. All the images were reviewed only once because of the large amount of work.