Dosage dans les milieux biologiques d'un nouveau bèta-bloquant, l'aténoiol, par chromatographie liquide haute performance

Decourt, S; Flouvat, B

doi:10.1016/s0021-9673(00)87065-x

Cited by 18 publications

(6 citation statements)

References 12 publications

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“…' the former ones (1,4,5). By employing buffers in the agar the standardization has been improved and false-positives diminished.…”

Section: Discussionmentioning

confidence: 98%

“…The 20% homogenates (w/v) of kidney and muscle were made with phosphate buffers of pH 6.0 (8.2 g KH2PO4+ 1.8 g K2HPO4/litre) and 8.0 (0.75 g KH2PO4 + 16.4 g K2HPO4/fitre). The large plate-agar-diffusion method was performed (4). After solidification of the agar poured out into the plates, 64 holes (9 mm in diameter) were punched into the agar and filled in duplicate with 0.1 ml of standard drug solutions.…”

Section: Sensitivity Testingmentioning

confidence: 99%

“…Anionic metabolites will not contribute, since they are not extracted from the alkaline homogenate. INTRODUCTION Recently, bioassay methods currently available for monitoring antimicrobial residues in edible tissues and milk were improved with respect to sulphonamide sensitivity by exploiting the synergistic effect between trimethoprim and sulfonamides (1,4,5). For sulphonamide residues the sensitivity of the methods ranged from 0.3 to 5 pg/ml.…”

mentioning

confidence: 99%

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An improved bioassay for the qualitative detection of sulphonamide and dapsone residues

Nouws¹,

Driessens²,

Smulders³

et al. 1985

Veterinary Quarterly

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“…' the former ones (1,4,5). By employing buffers in the agar the standardization has been improved and false-positives diminished.…”

Section: Discussionmentioning

confidence: 98%

Section: Sensitivity Testingmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

An improved bioassay for the qualitative detection of sulphonamide and dapsone residues

Nouws¹,

Driessens²,

Smulders³

et al. 1985

Veterinary Quarterly

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“…The procedures most widely used for measuring propranolol-type compounds in human plasma and urine at a 10 ppb level are high pressure liquid chromatography (3,4,5) and thin-layer chromatography (6) with spectrophotometric or fluorimetric detection. Electron-capture gas liquid chromatography (7) has also been used.…”

Section: Ch 2 Ch Ch3mentioning

confidence: 99%

“…Recently, bioassay methods currently available for monitoring antimicrobial residues in edible tissues and milk were improved with respect to sulphonamide sensitivity by exploiting the synergistic effect between trimethoprim and sulfonamides (1,4,5). For sulphonamide residues the sensitivity of the methods ranged from 0.3 to 5 pg/ml.…”

Section: Introductionmentioning

confidence: 99%

Simple fluorimetric screening for carazolol in swine kidneys bij means of Sep‐Pak cartridges

Engelsma

Simons

1985

Veterinary Quarterly

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High‐performance liquid chromatographic determination of β‐adrenoceptor blocking agents in body fluids

Šoltés

1989

Biomedical Chromatography

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Several reports have been published reviewing high-performance liquid chromatographic (HPLC) methods for the determination of beta-adrenoceptor blocking agents (beta-blockers) in biological materials (Flouvat et al., 1981; Mehta, 1983; Marko and Soltés, 1984; Ahnoff et al., 1985; Tkaczyková and Safarík, 1987). Of these, the paper by Mehta (1983) briefly summarizes the interrelationship between physiocochemical properties of beta-blockers with prechromatographic treatment of biological samples, as well as with the HPLC methods used for the determination of 12 beta-adrenoceptor blocking drugs. The work by Ahnoff et al. (1985) concerning the monitoring of cardiovascular drugs also deals with HPLC assays of 18 beta-blockers in plasma. The Appendix to this report presents the great majority of HPLC methods for determining 30 beta-blockers in various body fluids. HPLC methods providing resolution and determination of individual beta-blocker enantiomers have not been included since this topic is being covered by Walle and Walle (1989). The Appendix is just a guide to the methods reviewed for the HPLC determination of parent beta-blockers as well as some of their metabolites co-assayed in various body fluids. It does not include details such as the internal standard, recovery, setting of the detector, limit of determination, etc., given in the individual methods listed. The isolation technique of the drug(s) from the given body fluid represents the main step in the sample work-up procedure. Along with this information, only the type of the HPLC column packing and the detection principle used by each method's developers are given.

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Dosage dans les milieux biologiques d'un nouveau bèta-bloquant, l'aténoiol, par chromatographie liquide haute performance

Cited by 18 publications

References 12 publications

An improved bioassay for the qualitative detection of sulphonamide and dapsone residues

An improved bioassay for the qualitative detection of sulphonamide and dapsone residues

Simple fluorimetric screening for carazolol in swine kidneys bij means of Sep‐Pak cartridges

High‐performance liquid chromatographic determination of β‐adrenoceptor blocking agents in body fluids

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