Dosimeter Gel and MR Imaging for Verification of Calculated Dose Distributions in Clinical Radiation Therapy

Johansson, Sven; Magnusson, Peter; Fransson, Annette; Olsson, Lars; Christoffersson, J.-O.; Montelius, Anders; Mattsson, Sören

doi:10.3109/02841869709001264

Cited by 27 publications

(15 citation statements)

References 29 publications

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“…An alternative approach would be to use gel dosimeters 19 , 20 , 21 . Dosimetric cryogels are flexible materials that conform easily to curved regions of the body.…”

Section: Introductionmentioning

confidence: 99%

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Translucent poly(vinyl alcohol) cryogel dosimeters for simultaneous dose buildup and monitoring during chest wall radiation therapy

Eyadeh

Weston

Juhász

et al. 2016

J Applied Clin Med Phys

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Chest wall radiation therapy treatment delivery was monitored using a 5 mm thick radiochromic poly(vinyl alcohol) cryogel that also provided buildup material. The cryogels were used to detect positioning errors and measure the impact of shifts for a chest wall treatment that was delivered to a RANDO phantom. The phantom was shifted by ±2,±3, and ±5 mm from the planned position in the anterior/posterior (A/P) direction; these shifts represent setup errors and the uncertainty associated with lung filling during breath‐hold. The two‐dimensional absolute dose distributions measured in the cryogel at the planned position were compared with the distributions at all shifts from this position using gamma analysis (3%/3 mm, 10% threshold). For shifts of ±2,±3, and ±5 mm the passing rates ranged from 94.3% to 95.6%, 74.0% to 78.8%, and 17.5% to 22.5%, respectively. These results are consistent with the same gamma analysis performed on dose planes calculated in the middle of the cryogel and on the phantom surface using our treatment planning system, which ranged from 94.3% to 95.0%, 76.8% to 77.9%, and 23.5% to 24.3%, respectively. The Pinnacle dose planes were then scaled empirically and compared to the cryogel measurements. Using the same gamma metric, the pass rates ranged from 97.0% to 98.4%. The results of this study suggest that cryogels may be used as both a buildup material and to evaluate errors in chest wall treatment positioning during deep‐inspiration breath‐hold delivery. The cryogels are sensitive to A/P chest wall shifts of less than 3 mm, which potentially allows for the detection of clinically relevant errors.PACS number(s): 87.55.km, 87.57.uq

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“…An alternative approach would be to use gel dosimeters 19 , 20 , 21 . Dosimetric cryogels are flexible materials that conform easily to curved regions of the body.…”

Section: Introductionmentioning

confidence: 99%

“…In regions where the surface dose is of interest, a dosimetric cryogel may provide an accurate estimation of superficial dose distributions. Cryogels may also be used to quantify uncertainties in setup or field conjunctioning, and breathing irregularities during left breast or chest wall DIBH radiation therapy 20 , 21 …”

Section: Introductionmentioning

confidence: 99%

Translucent poly(vinyl alcohol) cryogel dosimeters for simultaneous dose buildup and monitoring during chest wall radiation therapy

Eyadeh

Weston

Juhász

et al. 2016

J Applied Clin Med Phys

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“…Karger et al (1999) used an array of up to 24 pinpoint ionization chambers for 3D dose verification. Gel and radiochromic dosimeters can be used to reconstruct high-resolution 3D dose distributions for proton beams (Johansson et al , 1997; Zhao et al , 2012). However, dosimetric gels can be difficult to work with, requiring careful preparation and handling procedures.…”

Section: Introductionmentioning

confidence: 99%

3D reconstruction of scintillation light emission from proton pencil beams using limited viewing angles—a simulation study

2014

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An accurate and high-resolution quality assurance (QA) method for proton radiotherapy beams is necessary to ensure correct dose delivery to the target. Detectors based on a large volume of liquid scintillator have shown great promise in providing fast and high-resolution measurements of proton treatment fields. However, previous work with these detectors has been limited to two-dimensional measurements, and the quantitative measurement of dose distributions was lacking. The purpose of the current study is to assess the feasibility of reconstructing three-dimensional (3D) scintillation light distributions of spot scanning proton beams using a scintillation system. The proposed system consists of a tank of liquid scintillator imaged by charge-coupled device cameras at three orthogonal viewing angles. Because of the limited number of viewing angles, we developed a profile-based technique to obtain an initial estimate that can improve the quality of the 3D reconstruction. We found that our proposed scintillator system and profile-based technique can reconstruct a single energy proton beam in 3D with a gamma passing rate (3%/3 mm local) of 100.0%. For asingle energy layer of an intensity modulated proton therapy prostate treatment plan, the proposed method can reconstruct the 3D light distribution with a gamma pass rate (3%/3 mm local) of 99.7%. In addition, we also found that the proposed method is effective in detecting errors in the treatment plan, indicating that it can be a very useful tool for 3D proton beam QA.

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“…matrix resulting from subtracting the calculated dose matrix from the FeMRI measured dose matrix could also be used to evaluate the application. For visualization purposes, the deviation matrix could be coded using a colour scale (5).…”

Section: Resultsmentioning

confidence: 99%

“…The deviations could have different origins, as shortcomings of both detector and TPS system. Deviations can be enhanced or cancelled, particularly if several treatment beams are superimposed (5). Hence, before setting up complex treatment techniques using FeMRI, it is very important to investigate the dosimetry system in simple and well-defined radiation beams.…”

Section: Resultsmentioning

confidence: 99%

Verification of Single Beam Treatment Planning Using a Ferrous Dosimeter Gel and MRI (FeMRI)

et al. 1998

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Dosimeter Gel and MR Imaging for Verification of Calculated Dose Distributions in Clinical Radiation Therapy

Cited by 27 publications

References 29 publications

Translucent poly(vinyl alcohol) cryogel dosimeters for simultaneous dose buildup and monitoring during chest wall radiation therapy

Translucent poly(vinyl alcohol) cryogel dosimeters for simultaneous dose buildup and monitoring during chest wall radiation therapy

3D reconstruction of scintillation light emission from proton pencil beams using limited viewing angles—a simulation study

Verification of Single Beam Treatment Planning Using a Ferrous Dosimeter Gel and MRI (FeMRI)

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