2017
DOI: 10.1016/j.adro.2017.03.006
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Dosimetric and clinical outcomes after volumetric modulated arc therapy for carcinoma of the thoracic esophagus

Abstract: PurposeThe efficiency of radiation delivery via volumetric modulated arc therapy (VMAT) is indisputable, but outcomes after VMAT for thoracic esophageal carcinoma are largely unknown.Methods and materialsWe retrospectively analyzed 65 patients with thoracic esophageal cancer who received VMAT to 50.4 Gy (range, 45-50.4 Gy) with concurrent chemotherapy from November 2012 to March 2016 at a single tertiary cancer center. We then used propensity score matching to match these 65 patients with 130 other patients tr… Show more

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Cited by 10 publications
(9 citation statements)
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“…Radiation pneumonitis is common in lung cancer but is much less so in EC because the radiation dose is lower than those used for lung cancer [12]. Some studies have reported lung dose to be an independent predictor of survival in patients with lung cancer [11], [13], but whether it affects survival in patients with EC is unknown.…”
Section: Introductionmentioning
confidence: 99%
“…Radiation pneumonitis is common in lung cancer but is much less so in EC because the radiation dose is lower than those used for lung cancer [12]. Some studies have reported lung dose to be an independent predictor of survival in patients with lung cancer [11], [13], but whether it affects survival in patients with EC is unknown.…”
Section: Introductionmentioning
confidence: 99%
“…Major prognostic factors associated with better OS on multivariate analysis were stages I and II patients ( P = .03) and radiation technique using arc therapy ( P = .04) (Appendix 1). Xu et al [24] found that, compared with step-and-shoot IMRT, volumetric arc therapy had better target conformity. Choi et al [25] found superior conformity index and conformation number in modulated arc therapy compared to step-and-shoot IMRT.…”
Section: Discussionmentioning
confidence: 99%
“…The current literature rationalizes the increasing use of IMRT. [4][5][6] In contrast, IMRT requires more precise mechanisms in the planning and treatment process with regard to smaller safety margins. Thus, 4-dimensional CT is useful to consider movements secondary to respiration, circulation, or peristalsis.…”
Section: Discussionmentioning
confidence: 99%