Dosimetric comparison of vaginal vault brachytherapy vs applicator-guided stereotactic body radiotherapy with volumetric modulated arc therapy and helical tomotherapy for endometrium cancer patients

The value of brachytherapy in the age of advanced external beam radiotherapy: a review of the literature in terms of dosimetry

“…However, the integral dose was 7.2% higher for IMRT. For most parameters, Yildrim et al [39] found very similar results with comparative dosimetry between BT, VMAT and HT for 12 patients, except for bladder D2cm3, which was significantly lower for BT. Recently, a study on irradiation of the vaginal cuff with VMAT and BT in postoperative endometrial cancer was published [37].…”

“…Interestingly, for irradiation of the vaginal cuff, EBRT techniques performed better than BT in terms of dose to OARs [37][38][39][40]. This is probably due to the fact that in BT, the dose is prescribed relatively far from the HDR source (2.5-3.5 cm) and the inverse square law is no longer of much advantage at this distance, especially considering that the OARs (rectum, bladder) are very close to the target volume.…”

Physical and Dosimetric Aspects of the Iridium-Knife

“…In this article, we review dosimetric studies for prostate, liver, endometrium, and intrathoracic malignancies either clinically performed with HDR BT and afterward virtually planned with SBRT or vice versa (8)(9)(10)(11)(12)(13)(14)(15). The dosimetric comparison for PTV coverage, organs at risk (OARs) dose sparing, plan conformity, dose heterogeneity, dose fall-off sharpness, and low dose spill are presented with the aid of dose-volume and physical quantities presented in Table 2.…”

“…A number of investigators performed retrospective studies to dosimetrically compare HDR BT and SBRT sequential boost in the treatment of gynecologic malignancies, and two representative investigations are discussed herein ( 13 , 14 ).…”

“…Yildirim et al. ( 14 ) recently performed a similar retrospective dosimetric study comparing HDR BT plans against SBRT plans designed with VMAT technique on a conventional linear accelerator (Axesse, Elekta AB, Stockholm, Sweden) and on a Hi-Art Tomotherapy system (TomoTherapy Inc., Madison, WI). Twelve patients with early-stage endometrial cancer previously treated postoperatively with HDR BT were included and for which SBRT plans were retrospectively created with the two abovementioned technologies.…”