Dosimetric experience with 2 commercially available multilumen balloon-based brachytherapy to deliver accelerated partial-breast irradiation

Fu, Weihua; Kim, Jong Oh; Chen, Alex S.J.; Mehta, Kiran; Pucci, Pietro; Huq, M. Saiful

doi:10.1016/j.meddos.2014.11.005

Cited by 2 publications

(1 citation statement)

References 36 publications

(39 reference statements)

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“…Hence, the skin maximum point dose was limited to ≤ 145% of the prescribed dose in the use of a single-lumen MammoSite® balloon applicator (Hologic Inc., Bedford, MA, USA) [10]. Later, with multi-lumen balloon (MLB) applicators such as MammoSite® MLB (Hologic Inc.) and Contura® (Hologic Inc.), the skin maximum point dose was restricted to ≤ 125% of the prescribed dose [11,12]. Furthermore, the strut-adjusted volume implant applicator, SAVI® (Cianna Medical, Aliso Viejo, CA, USA), which is a single entry interstitial applicator (nonballoon), was able to reduce the maximum skin dose constraint to 100% of the prescribed dose [13].…”

Section: Introductionmentioning

confidence: 99%

Relationship among different skin dose definitions in high-dose-rate (HDR) balloon breast brachytherapy

et al. 2018

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Objective To establish the relationship among various skin dosimetric indices and different volumetric definitions of skin in highdose-rate (HDR) balloon breast brachytherapy. Methods Fifty breast cancer patients were treated with HDR balloon brachytherapy. The MammoSite® applicator was used for 40 patients and the Contura® applicator for 10 patients. Skin structure was retrospectively defined by expanding the skin surface internal to the body with a thickness of 1, 2, 3, 4, or 5 mm in one method. In another method, the skin was defined by expanding its external to the body to demonstrate the maximum point dose on the skin surface. For each skin structure defined by six different methods, three dosimetric data points extracted from dose-volume histograms were compared. Dmax was defined as the maximum point dose, and D1cc and D0.1cc were defined as the minimum dose to 1 cm 3 and 0.1 cm 3 of the most irradiated skin volume, respectively. The relationship among 18 dosimetric parameters was presented in graphs, and linear curve fitting was performed to provide mathematical formulas. Results For each skin definition, the Dmax, D1cc, and D0.1cc values show a linear relationship such that Dmax is the largest, D0.1cc is the next, and D1cc is the smallest value. For each dosimetric parameter, there was a linear relationship among the dosimetric indices for 6 different skin definitions. For clinical use, all linear relationships were displayed in graphs and two parameters for linear fitting were provided. Average R 2 value for curve fitting was 0.978. ConclusionThe presented relationships can be developed in each individual institution and convert one dosimetric index to another for different skin definitions.

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