Dosimétrie biologique en cas d’exposition radiologique d’un grand nombre d’individus : apport de la détection automatique des dicentriques

Abstract

RÉSUMÉFollowing large-scale accidental overexposure to ionising radiation, a rapid triage of the exposed population can be performed by scoring dicentrics and ring chromosomes in 50 metaphases. This is rapid but not accurate. Following this triage step, the dose can be estimated by scoring 500 metaphases. This is lengthy but very accurate. To improve the methodology, we propose using software for automatic dicentric scoring, which was tested on 63 victims of a radiological accident. The method using automatic dicentric scoring was compared with the standard methods of manual scoring. The comparison of the doses obtained shows that the automatic method could replace the two steps of the manual scoring (50 and 500 metaphases). In fact, the automatic scoring method is more accurate than the manual scoring of 50 metaphases and can therefore be used for triage.