Dosing obese cats based on body weight spuriously affects some measures of glucose tolerance

Reeve-Johnson, M. K.; Rand, J. S.; Anderson, Stephen; Appleton, D. J.; Morton, John M.; Vankan, D.

doi:10.1016/j.domaniend.2016.05.007

Cited by 1 publication

(1 citation statement)

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“…In cats, administration of oral glucose requires careful handling techniques to minimize struggling and stress hyperglycaemia [19] and therefore intravenous glucose is used. Selection of a glucose concentration based on body weight, however, may lead to an overestimation in obese cats, and thereby an overdiagnosis of impaired glucose tolerance [20]. The lack of glucokinase in cats may account for a prolonged elevation of blood glucose after a meal [21] and needs to be considered in tests of glucose clearance.…”

Section: Diabetes Mellitusmentioning

confidence: 99%

Feline obesity and diabetes: a One Health perspective.

Lewitt¹

2019

CABI Reviews

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There is increasing awareness of obesity and diabetes mellitus in cats that parallels the 'epidemic' of obesity and type 2 diabetes in humans. Likewise, understanding of the pathophysiology and management of feline obesity and diabetes has developed alongside and draws from human medicine. As in human medicine, overweight and obesity are associated with the development with diabetes; however, there are other genetic and environmental influences that contribute to this risk, some of which are shared. In cats, the body condition score appears to be a good diagnostic tool. It is reliable in the hands of owners and is likely to reflect visceral adiposity. However, the diagnostic label of feline obesity should be considered against the rate of success of any intervention, owner perspectives and impact on cat quality of life, as well as risk of future disease. The classification of human diabetes is evolving towards one that is more closely linked to disease outcome and therefore management. Consideration could be given to classifying the diabetes of hypersomatotropism and that associated with exogenous glucocorticoid administration in cats, separately in veterinary medicine. Rather regarding feline obesity and diabetes as models of human disease, a closer interdisciplinary 'One Health' approach between veterinary and human medicine is warranted to advance research and clinical care in this field.

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Section: Diabetes Mellitusmentioning

confidence: 99%

Feline obesity and diabetes: a One Health perspective.

Lewitt¹

2019

CABI Reviews

View full text Add to dashboard Cite

show abstract

Dosing obese cats based on body weight spuriously affects some measures of glucose tolerance

Cited by 1 publication

References 39 publications

Feline obesity and diabetes: a One Health perspective.

Feline obesity and diabetes: a One Health perspective.

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